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HE hemagglutinin-esterase glycoprotein [ Human coronavirus HKU1 ]

Gene ID: 3200425, updated on 18-Aug-2023

Summary

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Gene symbol
HE
Gene description
hemagglutinin-esterase glycoprotein
Locus tag
HCHV1gp2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Human coronavirus HKU1 (isolate: HKU1, nat-host: Homo sapiens)
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Embecovirus
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Genomic context

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Sequence:
NC_006577.2 (21773..22933)

NC_006577.2Genomic Context describing neighboring genes Neighboring gene ORF1a polyprotein;ORF1ab polyprotein Neighboring gene spike glycoprotein Neighboring gene non-structural protein Neighboring gene envelope protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_006577.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans. Hurdiss DL, et al. Nat Commun, 2020 Sep 16. PMID 32938911, Free PMC Article
  2. Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation. Bakkers MJ, et al. Proc Natl Acad Sci U S A, 2016 May 31. PMID 27185912, Free PMC Article
  3. Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. Woo PC, et al. J Virol, 2005 Jan. PMID 15613317, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.
    Title: Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.
  2. Coronavirus receptor switch is explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
    Title: Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
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General gene information

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Homology

General protein information

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Preferred Names
hemagglutinin-esterase glycoprotein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006577.2 Reference assembly

    Range
    21773..22933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_173237.1 hemagglutinin-esterase glycoprotein [Human coronavirus HKU1]

    See identical proteins and their annotated locations for YP_173237.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q5MQD1
    UniProtKB/TrEMBL
    A0A140H1H0, E0YJ43, Q0ZJ86, Q0ZJB8, Q0ZJC6, S5ZBQ3
    Conserved Domains (1) summary
    cl28016
    Location:16 → 343
    Hema_HEFG; Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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