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CG33178 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318913, updated on 28-Oct-2024

Summary

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Official Symbol
CG33178provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0053178
Locus tag
Dmel_CG33178
See related
AllianceGenome:FB:FBgn0053178
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH14671; CG5579; Dmel\CG33178
Summary
Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in mitochondrion. Is expressed in adult head; embryonic head sensory system; and larval labral sensory complex. Orthologous to several human genes including MGST1 (microsomal glutathione S-transferase 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See CG33178 in Genome Data Viewer
Location:
13A9-13A9; 1-49 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15082827..15084017)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14976860..14978050)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44662 Neighboring gene long non-coding RNA:CR44661 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44960 Neighboring gene Cytochrome c oxidase copper chaperone COX17 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A combined computational strategy of sequence and structural analysis predicts the existence of a functional eicosanoid pathway in Drosophila melanogaster. Scarpati M, et al. PLoS One, 2019. PMID 30753230, Free PMC Article
  2. Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila. Gallach M, et al. Genome Biol Evol, 2010. PMID 21037198, Free PMC Article
  3. RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Jones CI, et al. Nucleic Acids Res, 2016 Jan 8. PMID 26656493, Free PMC Article
  4. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glutathione peroxidase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables glutathione transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in glutathione metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG33178-PA
CG33178-PB
CG33178-PC
NP_001285263.1
NP_001285264.1
NP_788904.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15082827..15084017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298335.1 → NP_001285264.1  uncharacterized protein Dmel_CG33178, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285264.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SY97
    Conserved Domains (1) summary
    pfam01124
    Location:29 → 159
    MAPEG; MAPEG family

  2. NM_001298334.1 → NP_001285263.1  uncharacterized protein Dmel_CG33178, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285263.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JF29
    Conserved Domains (1) summary
    pfam01124
    Location:29 → 171
    MAPEG; MAPEG family

  3. NM_176731.2 → NP_788904.1  uncharacterized protein Dmel_CG33178, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788904.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SY97
    Related
    FBpp0073780
    Conserved Domains (1) summary
    pfam01124
    Location:29 → 159
    MAPEG; MAPEG family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SY97 Q8SY97
X2JF29 X2JF29

Gene LinkOut

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