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Ost48 Oligosaccharyltransferase 48kD subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31849, updated on 2-Nov-2024

Summary

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Official Symbol
Ost48provided by FlyBase
Official Full Name
Oligosaccharyltransferase 48kD subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0014868
Locus tag
Dmel_CG9022
See related
AllianceGenome:FB:FBgn0014868
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Liang-1.11; CG9022; clone 1.11; Dmel\CG9022; DmOST50; DrOST; OST; ost48; OST48; OST48/WBP1; Ots48
Summary
Predicted to be involved in protein N-linked glycosylation via asparagine. Located in endomembrane system. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; gland; gut section; and mesoderm. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Orthologous to human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See Ost48 in Genome Data Viewer
Location:
8C14-8C14; 1-26 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9156929..9158515, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9050962..9052548, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Brahma associated protein 111kD Neighboring gene Histone H3.3B Neighboring gene Dorsal interacting protein 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit A3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in protein N-linked glycosylation via asparagine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation via asparagine IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
oligosaccharyltransferase 48kD subunit
Names
CG9022-PA
Ost48-PA
oligosaccaryltransferase 48kDa subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    9156929..9158515 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078541.4 → NP_511096.2  oligosaccharyltransferase 48kD subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511096.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24319, Q24355, Q9W382
    Related
    FBpp0071279
    Conserved Domains (1) summary
    pfam03345
    Location:27 → 437
    DDOST_48kD; Oligosaccharyltransferase 48 kDa subunit beta
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q24319.2 Q24319

Gene LinkOut

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