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CG7766 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31839, updated on 2-Nov-2024

Summary

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Official Symbol
CG7766provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030087
Locus tag
Dmel_CG7766
See related
AllianceGenome:FB:FBgn0030087
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7766
Summary
Predicted to enable calmodulin binding activity. Predicted to be involved in positive regulation of glycogen catabolic process. Predicted to be part of phosphorylase kinase complex. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXa; and glycogen storage disease IXd. Orthologous to human PHKA1 (phosphorylase kinase regulatory subunit alpha 1) and PHKA2 (phosphorylase kinase regulatory subunit alpha 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See CG7766 in Genome Data Viewer
Location:
8C8-8C9; 1-26 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9093612..9103739, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8987645..8997772, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Chaperonin containing TCP1 subunit 2 Neighboring gene mir-13b-2 stem loop Neighboring gene Bx42 Neighboring gene ADP-ribosylation factor related protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Larschan E, et al. Mol Cell, 2007 Oct 12. PMID 17936709
  2. Parallel and population-specific gene regulatory evolution in cold-adapted fly populations. Huang Y, et al. Genetics, 2021 Jul 14. PMID 33989401, Free PMC Article
  3. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Wang CI, et al. Nat Struct Mol Biol, 2013 Feb. PMID 23295261, Free PMC Article
  4. Drosophila melanogaster males respond differently at the behavioural and genome-wide levels to Drosophila melanogaster and Drosophila simulans females. Ellis LL, et al. J Evol Biol, 2009 Nov. PMID 19765174
  5. An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance. Lebo DPV, et al. G3 (Bethesda), 2021 Feb 9. PMID 33693600, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycogen metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of glycogen catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of phosphorylase kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7766-PA
CG7766-PB
CG7766-PC
CG7766-PD
CG7766-PG
CG7766-PH
CG7766-PI

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    9093612..9103739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298107.1 → NP_001285036.1  uncharacterized protein Dmel_CG7766, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285036.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D0IQI4, X2JJ32
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  2. NM_176716.4 → NP_788889.2  uncharacterized protein Dmel_CG7766, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788889.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    D0IQI4
    Related
    FBpp0071287
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  3. NM_001258658.2 → NP_001245587.1  uncharacterized protein Dmel_CG7766, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245587.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D0IQI4, M9NGW5
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  4. NM_001258659.2 → NP_001245588.1  uncharacterized protein Dmel_CG7766, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245588.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D0IQI4, M9NDS5
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  5. NM_001144708.3 → NP_001138180.1  uncharacterized protein Dmel_CG7766, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138180.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z134, D0IQI4
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  6. NM_132297.6 → NP_572525.3  uncharacterized protein Dmel_CG7766, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572525.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86B60, Q95TZ6, Q9W391
    UniProtKB/TrEMBL
    D0IQI4
    Related
    FBpp0071286
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15

  7. NM_001144707.3 → NP_001138179.1  uncharacterized protein Dmel_CG7766, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138179.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D0IQI4, Q6IDE0
    Conserved Domains (1) summary
    pfam00723
    Location:8 → 439
    Glyco_hydro_15; Glycosyl hydrolases family 15
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7Z134 B7Z134
M9NDS5 M9NDS5
M9NGW5 M9NGW5
Q6IDE0 Q6IDE0
Q9W391.2 Q9W391
X2JJ32 X2JJ32

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