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Ppt1 - Palmitoyl-protein thioesterase 1

Enables palmitoyl-(protein) hydrolase activity. Involved in several processes, including determination of adult lifespan; neuron fate specification; and positive regulation of synaptic vesicle endocytosis. Located in lysosome. Is expressed in several structures, including adult heart; anterior-posterior subdivision of organism; gonad; larval brain; and larval central nervous system. Used to study neuronal ceroid lipofuscinosis and neuronal ceroid lipofuscinosis 1. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa