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CG12081 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31799, updated on 2-Nov-2024

Summary

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Official Symbol
CG12081provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030053
Locus tag
Dmel_CG12081
See related
AllianceGenome:FB:FBgn0030053
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12081
Summary
Predicted to enable chromatin binding activity. Predicted to be located in chromatin. Predicted to be active in cytoplasm. Is expressed in organism. Orthologous to human KLHDC3 (kelch domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG12081 in Genome Data Viewer
Location:
7F7-7F7; 1-23 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8588811..8590774)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8482844..8484807)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Serine Protease Immune Response Integrator Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organization of the sex-ratio meiotic drive region in Drosophila simulans. Montchamp-Moreau C, et al. Genetics, 2006 Nov. PMID 16387875, Free PMC Article
  2. Systematic identification of functional orthologs based on protein network comparison. Bandyopadhyay S, et al. Genome Res, 2006 Mar. PMID 16510899, Free PMC Article
  3. The chromosomal high-affinity binding sites for the Drosophila dosage compensation complex. Straub T, et al. PLoS Genet, 2008 Dec. PMID 19079572, Free PMC Article
  4. Transcriptional regulators form diverse groups with context-dependent regulatory functions. Stampfel G, et al. Nature, 2015 Dec 3. PMID 26550828
  5. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in chromatin ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12081-PA
CG12081-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    8588811..8590774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272414.1 → NP_001259343.1  uncharacterized protein Dmel_CG12081, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259343.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3D5
    Conserved Domains (5) summary
    sd00038
    Location:13 → 69
    Kelch; KELCH repeat [structural motif]
    pfam01344
    Location:78 → 117
    Kelch_1; Kelch motif
    pfam13415
    Location:137 → 188
    Kelch_3; Galactose oxidase, central domain
    pfam13854
    Location:237 → 276
    Kelch_5; Kelch motif
    pfam13964
    Location:13 → 60
    Kelch_6; Kelch motif

  2. NM_132266.2 → NP_572494.1  uncharacterized protein Dmel_CG12081, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572494.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3D5
    Related
    FBpp0071164
    Conserved Domains (5) summary
    sd00038
    Location:13 → 69
    Kelch; KELCH repeat [structural motif]
    pfam01344
    Location:78 → 117
    Kelch_1; Kelch motif
    pfam13415
    Location:137 → 188
    Kelch_3; Galactose oxidase, central domain
    pfam13854
    Location:237 → 276
    Kelch_5; Kelch motif
    pfam13964
    Location:13 → 60
    Kelch_6; Kelch motif
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3D5 Q9W3D5

Gene LinkOut

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