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FGFR4 fibroblast growth factor receptor 4 [ Bos taurus (domestic cattle) ]

Gene ID: 317696, updated on 4-Oct-2024

Summary

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Official Symbol
FGFR4provided by VGNC
Official Full Name
fibroblast growth factor receptor 4provided by VGNC
Primary source
VGNC:VGNC:28988
See related
Ensembl:ENSBTAG00000010543
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See FGFR4 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (38575626..38586374)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger protein 346 Neighboring gene methyltransferase N6AMT1-like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Somatic cell nuclear transfer is associated with altered expression of angiogenic factor systems in bovine placentomes at term. Campos DB, et al. Genet Mol Res, 2010 Feb 23. PMID 20198587
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor receptor 4
NP_001179513.1
XP_059743924.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192584.2 → NP_001179513.1  fibroblast growth factor receptor 4 precursor

    See identical proteins and their annotated locations for NP_001179513.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000007
    UniProtKB/TrEMBL
    F1MN51
    Related
    ENSBTAP00000013942.5, ENSBTAT00000013942.7
    Conserved Domains (6) summary
    cd05858
    Location:263 → 350
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    smart00408
    Location:50 → 107
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:161 → 240
    IG_like; Immunoglobulin like
    pfam07714
    Location:466 → 742
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:156 → 240
    Ig; Immunoglobulin domain
    cl21453
    Location:453 → 766
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    38575626..38586374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059887941.1 → XP_059743924.1  fibroblast growth factor receptor 4 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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