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MYH10 myosin heavy chain 10 [ Bos taurus (domestic cattle) ]

Gene ID: 317655, updated on 10-Oct-2024

Summary

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Official Symbol
MYH10provided by VGNC
Official Full Name
myosin heavy chain 10provided by VGNC
Primary source
VGNC:VGNC:31794
See related
BGD:BT23905; Ensembl:ENSBTAG00000021151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See MYH10 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
45
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (28061573..28183702, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein-like Neighboring gene ubiquitin-conjugating enzyme E2 B-like Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene ring finger protein 222 Neighboring gene uncharacterized LOC132343043 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil domain containing 42

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Neuronal cell expression of inserted isoforms of vertebrate nonmuscle myosin heavy chain II-B. Itoh K, et al. J Biol Chem, 1995 Jun 16. PMID 7782316
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin-10
Names
NMMHC II-b
NMMHC-B
NMMHC-IIB
cellular myosin heavy chain, type B
myosin heavy chain, non-muscle IIb
myosin, heavy polypeptide 10, non-muscle
non-muscle myosin heavy chain B
non-muscle myosin heavy chain IIb
nonmuscle myosin heavy chain B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174834.1 → NP_777259.1  myosin-10

    See identical proteins and their annotated locations for NP_777259.1

    Status: PROVISIONAL

    Source sequence(s)
    AB022023
    UniProtKB/Swiss-Prot
    Q27991
    UniProtKB/TrEMBL
    A0A452DIZ9
    Related
    ENSBTAP00000090309.1, ENSBTAT00000098818.1
    Conserved Domains (8) summary
    cd14920
    Location:99 → 771
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 771
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:848 → 1928
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1062 → 1093
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1111 → 1222
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1645 → 1696
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1769 → 1867
    DUF2570; Protein of unknown function (DUF2570)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    28061573..28183702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059877752.1 → XP_059733735.1  myosin-10 isoform X1

    UniProtKB/TrEMBL
    A0AAA9RT29

  2. XM_005220298.5 → XP_005220355.1  myosin-10 isoform X1

    See identical proteins and their annotated locations for XP_005220355.1

    UniProtKB/TrEMBL
    A0AAA9RT29, A0AAA9SL38
    Conserved Domains (8) summary
    cd14920
    Location:99 → 802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:879 → 1959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1093 → 1124
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1142 → 1253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1676 → 1727
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1800 → 1898
    DUF2570; Protein of unknown function (DUF2570)

  3. XM_005220299.5 → XP_005220356.1  myosin-10 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SL38
    Conserved Domains (8) summary
    cd14920
    Location:99 → 792
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 792
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:869 → 1949
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1083 → 1114
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1132 → 1243
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1666 → 1717
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1790 → 1888
    DUF2570; Protein of unknown function (DUF2570)

  4. XM_059877753.1 → XP_059733736.1  myosin-10 isoform X3

    UniProtKB/TrEMBL
    A0AAF7AA92
    Related
    ENSBTAP00000065840.2, ENSBTAT00000075528.2

  5. XM_005220297.5 → XP_005220354.1  myosin-10 isoform X1

    See identical proteins and their annotated locations for XP_005220354.1

    UniProtKB/TrEMBL
    A0AAA9RT29, A0AAA9SL38
    Related
    ENSBTAP00000075953.1, ENSBTAT00000132144.1
    Conserved Domains (8) summary
    cd14920
    Location:99 → 802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:879 → 1959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1093 → 1124
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1142 → 1253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1676 → 1727
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1800 → 1898
    DUF2570; Protein of unknown function (DUF2570)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27991.2 GenPept UniProtKB/Swiss-Prot:Q27991

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