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ttc27 tetratricopeptide repeat domain 27 [ Danio rerio (zebrafish) ]

Gene ID: 317640, updated on 17-Aug-2024

Summary

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Official Symbol
ttc27provided by ZNC
Official Full Name
tetratricopeptide repeat domain 27provided by ZNC
Primary source
ZFIN:ZDB-GENE-030102-1
See related
Ensembl:ENSDARG00000007918 AllianceGenome:ZFIN:ZDB-GENE-030102-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hi1257; chunp6906; flj20272l; im:7158386; wu:fj40h09
Summary
Is expressed in several structures, including alar plate midbrain region; head; immature eye; midbrain; and pectoral fin bud. Orthologous to human TTC27 (tetratricopeptide repeat domain 27). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
21
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (22760120..22946997)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (22740375..22927161)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene Yip1 domain family, member 4 Neighboring gene baculoviral IAP repeat containing 6 Neighboring gene birc6 antisense RNA 2 Neighboring gene microRNA 456 Neighboring gene latent transforming growth factor beta binding protein 1 Neighboring gene RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Golling G, et al. Nat Genet, 2002 Jun. PMID 12006978
  2. Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. Buono L, et al. Nat Commun, 2021 Jun 23. PMID 34162866, Free PMC Article
  3. A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Trinh le A, et al. Genes Dev, 2011 Nov 1. PMID 22056673, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tetratricopeptide repeat protein 27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173285.2 → NP_775392.2  tetratricopeptide repeat protein 27

    Status: VALIDATED

    Source sequence(s)
    BX511309, BX548077, CT027669
    UniProtKB/TrEMBL
    A0A8M1P826, K7DY99
    Related
    ENSDARP00000126427.1, ENSDART00000151999.2
    Conserved Domains (3) summary
    sd00006
    Location:560 → 586
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:560 → 591
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:560 → 622
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    22760120..22946997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467108.1 → XP_021322783.1  tetratricopeptide repeat protein 27 isoform X1

    UniProtKB/TrEMBL
    A0A8M9P8S5

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394987.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    141088..300563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395329.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    3581..84467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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