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Slc39a3 solute carrier family 39 member 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314637, updated on 2-Nov-2024

Summary

Official Symbol
Slc39a3provided by RGD
Official Full Name
solute carrier family 39 member 3provided by RGD
Primary source
RGD:1310863
See related
EnsemblRapid:ENSRNOG00000045524 AllianceGenome:RGD:1310863
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to act upstream of or within several processes, including T cell homeostasis; chordate embryonic development; and zinc ion transport. Predicted to be located in apical plasma membrane and hippocampal mossy fiber to CA3 synapse. Predicted to be active in plasma membrane. Orthologous to human SLC39A3 (solute carrier family 39 member 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 66.3), Brain (RPKM 59.8) and 9 other tissues See more
Orthologs
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Genomic context

See Slc39a3 in Genome Data Viewer
Location:
7q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9327541..9333542)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (8676845..8682846)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (11545073..11551074)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene thimet oligopeptidase 1 Neighboring gene uncharacterized LOC120093771 Neighboring gene small glutamine rich tetratricopeptide repeat co-chaperone alpha Neighboring gene uncharacterized LOC120093772 Neighboring gene DIRAS family GTPase 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC105842

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables zinc ion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in T cell homeostasis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within T cell homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in embryonic cranial skeleton morphogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within embryonic cranial skeleton morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in in utero embryonic development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
involved_in limb development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within limb development ISO
Inferred from Sequence Orthology
more info
 
involved_in zinc ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in zinc ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within zinc ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in zinc ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in zinc ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within zinc ion transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in hippocampal mossy fiber to CA3 synapse IEA
Inferred from Electronic Annotation
more info
 
located_in hippocampal mossy fiber to CA3 synapse ISO
Inferred from Sequence Orthology
more info
 
located_in hippocampal mossy fiber to CA3 synapse ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
zinc transporter ZIP3
Names
ZIP-3
solute carrier family 39 (zinc transporter), member 3
zrt- and Irt-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008356.1NP_001008357.1  zinc transporter ZIP3

    See identical proteins and their annotated locations for NP_001008357.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086411
    UniProtKB/Swiss-Prot
    Q5U1X7
    UniProtKB/TrEMBL
    A0A8I5ZVZ2, A6K8D4
    Related
    ENSRNOP00000066970.1, ENSRNOT00000073221.4
    Conserved Domains (1) summary
    pfam02535
    Location:5312
    Zip; ZIP Zinc transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9327541..9333542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)