U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rexo1 RNA exonuclease 1 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 314630, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Rexo1provided by RGD
Official Full Name
RNA exonuclease 1 homologprovided by RGD
Primary source
RGD:1309872
See related
EnsemblRapid:ENSRNOG00000017916 AllianceGenome:RGD:1309872
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tceb3bp1
Summary
Predicted to enable exonuclease activity. Predicted to be involved in rRNA 3'-end processing. Predicted to be located in nuclear body. Predicted to be active in nucleus. Orthologous to human REXO1 (RNA exonuclease 1 homolog). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 52.9), Testes (RPKM 47.6) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rexo1 in Genome Data Viewer
Location:
7q11
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (9804740..9824717)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (9154050..9174035)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (12022268..12041660)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 17A, depalmitoylase Neighboring gene KLF transcription factor 16 Neighboring gene uncharacterized LOC120093775 Neighboring gene uncharacterized LOC134479810 Neighboring gene ATPase phospholipid transporting 8B3 Neighboring gene one cut homeobox 3 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in rRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nuclear body IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
RNA exonuclease 1 homolog
Names
REX1, RNA exonuclease 1 homolog
transcription elongation factor B polypeptide 3 binding protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012114.3 → NP_001012114.2  RNA exonuclease 1 homolog

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A6K8J6, D3ZCX6
    Related
    ENSRNOP00000024080.5, ENSRNOT00000024080.8
    Conserved Domains (2) summary
    cd06145
    Location:1037 → 1185
    REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
    pfam15870
    Location:778 → 938
    EloA-BP1; ElonginA binding-protein 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    9804740..9824717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263421.1 → XP_063119491.1  RNA exonuclease 1 homolog isoform X1

RNA

  1. XR_005486604.2 RNA Sequence

  2. XR_005486605.2 RNA Sequence

  3. XR_010052967.1 RNA Sequence

  4. XR_005486606.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools