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Wdr89 WD repeat domain 89 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314243, updated on 2-Nov-2024

Summary

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Official Symbol
Wdr89provided by RGD
Official Full Name
WD repeat domain 89provided by RGD
Primary source
RGD:1307393
See related
EnsemblRapid:ENSRNOG00000021628 AllianceGenome:RGD:1307393
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307393
Summary
Predicted to act upstream of or within corpus callosum development and ventricular system development. Orthologous to human WDR89 (WD repeat domain 89). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 37.0), Spleen (RPKM 31.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Wdr89 in Genome Data Viewer
Location:
6q24
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (100086169..100117796, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (94350468..94382085, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (98599456..98631512, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit B', epsilon Neighboring gene uncharacterized LOC120093261 Neighboring gene uncharacterized LOC120103554 Neighboring gene cytochrome c oxidase subunit 7B, mitochondrial-like Neighboring gene sphingosine-1-phosphate phosphatase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC108878

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in corpus callosum development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within corpus callosum development ISO
Inferred from Sequence Orthology
more info
  
involved_in ventricular system development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ventricular system development ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
WD repeat-containing protein 89

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014078.2 → NP_001014100.1  WD repeat-containing protein 89

    See identical proteins and their annotated locations for NP_001014100.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/Swiss-Prot
    Q5FVP5
    UniProtKB/TrEMBL
    A6HC80
    Conserved Domains (3) summary
    COG2319
    Location:42 → 367
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:74 → 112
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:40 → 348
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    100086169..100117796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006240233.5 → XP_006240295.1  WD repeat-containing protein 89 isoform X2

    See identical proteins and their annotated locations for XP_006240295.1

    UniProtKB/TrEMBL
    A0A8L2Q2X8
    Related
    ENSRNOP00000006860.4, ENSRNOT00000006860.6
    Conserved Domains (3) summary
    COG2319
    Location:53 → 378
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:85 → 123
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:51 → 359
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_006240235.5 → XP_006240297.5  WD repeat-containing protein 89 isoform X1

    UniProtKB/Swiss-Prot
    Q5FVP5
    UniProtKB/TrEMBL
    A6HC80
    Related
    ENSRNOP00000108226.1, ENSRNOT00000168328.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5FVP5.1 GenPept UniProtKB/Swiss-Prot:Q5FVP5

Gene LinkOut

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