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CG32795 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31270, updated on 28-Oct-2024

Summary

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Official Symbol
CG32795provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0040384
Locus tag
Dmel_CG32795
See related
AllianceGenome:FB:FBgn0040384
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2716; CG2766; Dmel\CG32795; EG:BACN33B1.2
Summary
Involved in defense response to Gram-negative bacterium and positive regulation of innate immune response. Predicted to be active in membrane. Is expressed in adult head. Orthologous to human TMEM120A (transmembrane protein 120A) and TMEM120B (transmembrane protein 120B). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See CG32795 in Genome Data Viewer
Location:
3B6-3B6; 1-1.5 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2782906..2790567, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2676939..2684600, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43494 Neighboring gene kin of irre Neighboring gene Syntaxin 4 Neighboring gene uncharacterized protein Neighboring gene white

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Creation of a new system to study insulators in Drosophila melanogaster. Erokhin MM, et al. Dokl Biochem Biophys, 2009 Sep-Oct. PMID 20848905
  2. Molecular and bioinformatic analysis of the FB-NOF transposable element. Badal M, et al. Gene, 2006 Apr 12. PMID 16478650
  3. An FB-NOF mediated duplication of the white gene is responsible for the zeste1 phenotype in some Drosophila melanogaster unstable strains. Badal M, et al. Mol Genet Genomics, 2006 Jan. PMID 16333669
  4. Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster. LaFave MC, et al. Genetics, 2011 Jul. PMID 21527778, Free PMC Article
  5. Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs. Chetverina D, et al. Nucleic Acids Res, 2008 Feb. PMID 18086699, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium HMP PubMed 
involved_in positive regulation of innate immune response HMP PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32795-PA
CG32795-PB
CG32795-PC
CG32795-PD
CG32795-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2782906..2790567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258580.1 → NP_001245509.1  uncharacterized protein Dmel_CG32795, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245509.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
    UniProtKB/TrEMBL
    A4V3W8
    Conserved Domains (1) summary
    pfam07851
    Location:7 → 329
    TMPIT; TMPIT-like protein

  2. NM_166952.1 → NP_726830.1  uncharacterized protein Dmel_CG32795, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726830.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
    UniProtKB/TrEMBL
    A4V3W8
    Related
    FBpp0070469, FBtr0070491
    Conserved Domains (1) summary
    pfam07851
    Location:7 → 329
    TMPIT; TMPIT-like protein

  3. NM_206617.2 → NP_996340.1  uncharacterized protein Dmel_CG32795, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996340.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
    UniProtKB/TrEMBL
    A4V3W8
    Conserved Domains (1) summary
    pfam07851
    Location:7 → 329
    TMPIT; TMPIT-like protein

  4. NM_130673.4 → NP_570029.1  uncharacterized protein Dmel_CG32795, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_570029.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
    UniProtKB/TrEMBL
    A4V3W8
    Related
    FBpp0070470
    Conserved Domains (1) summary
    pfam07851
    Location:7 → 329
    TMPIT; TMPIT-like protein

  5. NM_001297905.1 → NP_001284834.1  uncharacterized protein Dmel_CG32795, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284834.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
    UniProtKB/TrEMBL
    A4V3W8
    Conserved Domains (1) summary
    pfam07851
    Location:7 → 329
    TMPIT; TMPIT-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4V3W8 A4V3W8
Q9U1M2.1 Q9U1M2

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