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Ugalt UDP-galactose transporter [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31255, updated on 28-Oct-2024

Summary

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Official Symbol
Ugaltprovided by FlyBase
Official Full Name
UDP-galactose transporterprovided by FlyBase
Primary source
FLYBASE:FBgn0024994
Locus tag
Dmel_CG2675
See related
AllianceGenome:FB:FBgn0024994
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-3Bb; CG2675; Csat; CSAT; Dmel\CG2675; DmNST; DmUGT; dNST-1; dNST-2; EG:100G10.5; UDP-Gal/UDP-GalNAc; ugt
Summary
Enables UDP-N-acetylgalactosamine transmembrane transporter activity and UDP-galactose transmembrane transporter activity. Involved in UDP-N-acetylgalactosamine transmembrane transport; UDP-galactose transmembrane transport; and galactose transmembrane transport. Located in Golgi medial cisterna. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIm. Orthologous to human SLC35A2 (solute carrier family 35 member A2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

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See Ugalt in Genome Data Viewer
Location:
3B2-3B2; 1-1.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2701124..2703852, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2595157..2597885, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Paraplegin Neighboring gene L(3)mbt interactor in ovarian somatic cells Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human and Drosophila UDP-galactose transporters transport UDP-N-acetylgalactosamine in addition to UDP-galactose. Segawa H, et al. Eur J Biochem, 2002 Jan. PMID 11784306
  2. Expression and functional characterization of a nucleotide sugar transporter from Drosophila melanogaster: relevance to protein glycosylation in insect cell expression systems. Aumiller JJ, et al. Protein Expr Purif, 2002 Dec. PMID 12460768, Free PMC Article
  3. Expression of a functional Drosophila melanogaster N-acetylneuraminic acid (Neu5Ac) phosphate synthase gene: evidence for endogenous sialic acid biosynthetic ability in insects. Kim K, et al. Glycobiology, 2002 Feb. PMID 11886840
  4. P-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic Drosophila melanogaster. Zehring WA, et al. Cell, 1984 Dec. PMID 6094014
  5. Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms. Reddy P, et al. Cell, 1984 Oct. PMID 6435882

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
NOT enables CMP-N-acetylneuraminate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-N-acetylgalactosamine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables UDP-galactose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-galactose transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
NOT enables UDP-glucuronic acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
NOT enables UDP-xylose transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyrimidine nucleotide-sugar transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
NOT involved_in CMP-N-acetylneuraminate transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in UDP-N-acetylgalactosamine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in UDP-galactose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in UDP-galactose transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in galactose transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi medial cisterna IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UDP-galactose transporter
Names
CG2675-PA
CG2675-PB
CG2675-PC
D.melanogaster nucleotide sugar transporter
UDP-Gal transporter
Ugalt-PA
Ugalt-PB
Ugalt-PC
csat

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2701124..2703852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001297904.1 → NP_001284833.1  UDP-galactose transporter, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284833.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W4W6
    Conserved Domains (2) summary
    pfam04142
    Location:7 → 331
    Nuc_sug_transp; Nucleotide-sugar transporter
    cl23754
    Location:90 → 330
    EamA; EamA-like transporter family

  2. NM_130663.4 → NP_570019.1  UDP-galactose transporter, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_570019.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W4W6
    Related
    FBpp0070478
    Conserved Domains (2) summary
    pfam04142
    Location:7 → 331
    Nuc_sug_transp; Nucleotide-sugar transporter
    cl23754
    Location:90 → 330
    EamA; EamA-like transporter family

  3. NM_001144677.3 → NP_001138149.1  UDP-galactose transporter, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138149.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76865
    Conserved Domains (2) summary
    pfam04142
    Location:18 → 342
    Nuc_sug_transp; Nucleotide-sugar transporter
    cl23754
    Location:101 → 341
    EamA; EamA-like transporter family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O76865 O76865
Q9W4W6 Q9W4W6

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