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Kbtbd4 kelch repeat and BTB domain containing 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311185, updated on 17-Aug-2024

Summary

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Official Symbol
Kbtbd4provided by RGD
Official Full Name
kelch repeat and BTB domain containing 4provided by RGD
Primary source
RGD:1310234
See related
EnsemblRapid:ENSRNOG00000009397 AllianceGenome:RGD:1310234
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human KBTBD4 (kelch repeat and BTB domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 108.2), Brain (RPKM 106.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Kbtbd4 in Genome Data Viewer
Location:
3q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (97339500..97345599)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (76883671..76889769)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (79728759..79735838)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 4 Neighboring gene family with sequence similarity 180 member B Neighboring gene NADH:ubiquinone oxidoreductase core subunit S3 Neighboring gene protein tyrosine phosphatase, mitochondrial 1 Neighboring gene eukaryotic translation elongation factor 1 gamma, pseudogene 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
kelch repeat and BTB domain-containing protein 4
Names
kelch repeat and BTB (POZ) domain containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399486.1 → NP_001386415.1  kelch repeat and BTB domain-containing protein 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6HN91
    Conserved Domains (4) summary
    PHA03098
    Location:47 → 479
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:279 → 314
    Kelch; KELCH repeat [structural motif]
    cd18272
    Location:13 → 152
    BTB_POZ_KBTBD4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)
    cd18481
    Location:142 → 229
    BACK_KBTBD4; BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)

  2. NM_001399487.1 → NP_001386416.1  kelch repeat and BTB domain-containing protein 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    97339500..97345599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234507.5 → XP_006234569.1  kelch repeat and BTB domain-containing protein 4 isoform X2

    See identical proteins and their annotated locations for XP_006234569.1

    UniProtKB/TrEMBL
    A6HN90
    Related
    ENSRNOP00000060210.2, ENSRNOT00000068124.4
    Conserved Domains (4) summary
    PHA03098
    Location:63 → 495
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:295 → 330
    Kelch; KELCH repeat [structural motif]
    cd18272
    Location:29 → 168
    BTB_POZ_KBTBD4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)
    cd18481
    Location:158 → 245
    BACK_KBTBD4; BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)

  2. XM_039104897.2 → XP_038960825.1  kelch repeat and BTB domain-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A6HN91
    Conserved Domains (4) summary
    PHA03098
    Location:47 → 479
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:279 → 314
    Kelch; KELCH repeat [structural motif]
    cd18272
    Location:13 → 152
    BTB_POZ_KBTBD4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)
    cd18481
    Location:142 → 229
    BACK_KBTBD4; BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)

  3. XM_039104898.2 → XP_038960826.1  kelch repeat and BTB domain-containing protein 4 isoform X4

    Conserved Domains (3) summary
    PHA03098
    Location:116 → 308
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:108 → 143
    Kelch; KELCH repeat [structural motif]
    cl28903
    Location:26 → 58
    BACK; BACK (BTB and C-terminal Kelch) domain

  4. XM_017591715.3 → XP_017447204.1  kelch repeat and BTB domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K102
    Related
    ENSRNOP00000071649.2, ENSRNOT00000084833.3
    Conserved Domains (4) summary
    PHA03098
    Location:82 → 514
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:314 → 349
    Kelch; KELCH repeat [structural motif]
    cd18272
    Location:48 → 187
    BTB_POZ_KBTBD4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)
    cd18481
    Location:177 → 264
    BACK_KBTBD4; BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein 4 (KBTBD4)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001107746.1: Suppressed sequence

    Description
    NM_001107746.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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