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Mcmbp minichromosome maintenance complex binding protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 309009, updated on 2-Nov-2024

Summary

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Official Symbol
Mcmbpprovided by RGD
Official Full Name
minichromosome maintenance complex binding proteinprovided by RGD
Primary source
RGD:1306730
See related
EnsemblRapid:ENSRNOG00000020394 AllianceGenome:RGD:1306730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
MCM-BP; RGD1306730
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in DNA-templated DNA replication and sister chromatid cohesion. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be part of MCM complex. Orthologous to human MCMBP (minichromosome maintenance complex binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 146.9), Spleen (RPKM 134.2) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mcmbp in Genome Data Viewer
Location:
1q37
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (192702383..192747381, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (183270598..183316975, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (200118226..200163106, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene BAG cochaperone 3 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene small nucleolar RNA SNORA36 family Neighboring gene SEC23 interacting protein Neighboring gene small nucleolar RNA U109

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC125204

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
  
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
  
enables chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA-templated DNA replication ISO
Inferred from Sequence Orthology
more info
  
involved_in DNA-templated DNA replication ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in sister chromatid cohesion IEA
Inferred from Electronic Annotation
more info
  
involved_in sister chromatid cohesion ISO
Inferred from Sequence Orthology
more info
  
involved_in sister chromatid cohesion ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of MCM complex IEA
Inferred from Electronic Annotation
more info
  
part_of MCM complex ISO
Inferred from Sequence Orthology
more info
  
part_of MCM complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cell junction IEA
Inferred from Electronic Annotation
more info
  
located_in cell junction ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mini-chromosome maintenance complex-binding protein
Names
MCM-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039608.2 → NP_001034697.2  mini-chromosome maintenance complex-binding protein

    See identical proteins and their annotated locations for NP_001034697.2

    Status: VALIDATED

    Source sequence(s)
    BC160884
    UniProtKB/Swiss-Prot
    B1H268
    UniProtKB/TrEMBL
    A0A8I5ZSQ3
    Related
    ENSRNOP00000027644.6, ENSRNOT00000027644.7
    Conserved Domains (1) summary
    pfam09739
    Location:36 → 628
    MCM_bind; Mini-chromosome maintenance replisome factor

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    192702383..192747381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039078498.2 → XP_038934426.1  mini-chromosome maintenance complex-binding protein isoform X1

    Conserved Domains (1) summary
    pfam09739
    Location:1 → 344
    MCM_bind; Mini-chromosome maintenance replisome factor
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B1H268.1 GenPept UniProtKB/Swiss-Prot:B1H268

Gene LinkOut

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