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Car11 carbonic anhydrase 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308588, updated on 2-Nov-2024

Summary

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Official Symbol
Car11provided by RGD
Official Full Name
carbonic anhydrase 11provided by RGD
Primary source
RGD:735155
See related
EnsemblRapid:ENSRNOG00000021017 AllianceGenome:RGD:735155
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ca11; CAR-XI
Summary
Predicted to enable hydro-lyase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in extracellular region. Predicted to be active in basolateral plasma membrane. Orthologous to human CA11 (carbonic anhydrase 11). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 177.4), Uterus (RPKM 52.2) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Car11 in Genome Data Viewer
Location:
1q22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (105306347..105311651)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (96169900..96175191)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101682009..101687358)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene fucosyltransferase 2 Neighboring gene secretory blood group 1 Neighboring gene netrin 5 Neighboring gene D-box binding PAR bZIP transcription factor Neighboring gene sphingosine kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney. Verlander JW, et al. Am J Physiol Renal Physiol, 2003 Feb. PMID 12388412
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC93050

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydro-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in one-carbon metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
carbonic anhydrase-related protein 11
Names
carbonic anhydrase-related XI protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175708.3 → NP_783639.1  carbonic anhydrase-related protein 11 precursor

    See identical proteins and their annotated locations for NP_783639.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086972
    UniProtKB/TrEMBL
    F7FEL0, Q811X3
    Related
    ENSRNOP00000028540.3, ENSRNOT00000028540.6
    Conserved Domains (1) summary
    cd03121
    Location:48 → 304
    alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    105306347..105311651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262113.1 → XP_063118183.1  carbonic anhydrase-related protein 11 isoform X2

  2. XM_063262112.1 → XP_063118182.1  carbonic anhydrase-related protein 11 isoform X1

  3. XM_017589148.3 → XP_017444637.1  carbonic anhydrase-related protein 11 isoform X3

    Related
    ENSRNOP00000102708.1, ENSRNOT00000165273.1

  4. XM_017589149.3 → XP_017444638.1  carbonic anhydrase-related protein 11 isoform X4

  5. XM_063262118.1 → XP_063118188.1  carbonic anhydrase-related protein 11 isoform X5

  6. XM_063262120.1 → XP_063118190.1  carbonic anhydrase-related protein 11 isoform X6

Nucleotide Protein Strain
Heading Accession and Version

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