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Slc17a2 solute carrier family 17, member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306950, updated on 20-Aug-2024

Summary

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Official Symbol
Slc17a2provided by RGD
Official Full Name
solute carrier family 17, member 2provided by RGD
Primary source
RGD:1308821
See related
EnsemblRapid:ENSRNOG00000017180 AllianceGenome:RGD:1308821
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable sialic acid transmembrane transporter activity. Predicted to be involved in sialic acid transport. Predicted to be active in lysosome. Predicted to be integral component of plasma membrane. Orthologous to human SLC17A2 (solute carrier family 17 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 311.5), Kidney (RPKM 89.2) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See Slc17a2 in Genome Data Viewer
Location:
17p11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (41748195..41767601, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (41318312..41339012, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (43567528..43584228, complement)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 17 member 1 Neighboring gene uncharacterized LOC134482855 Neighboring gene solute carrier family 17 member 3 Neighboring gene H1.1 linker histone, cluster member Neighboring gene tripartite motif containing 38 Neighboring gene histone H4C like 1 Neighboring gene H3 clustered histone 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables urate transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in monoatomic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in urate transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sodium-dependent phosphate transport protein 3
Names
solute carrier family 17 (sodium phosphate), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107353.2 → NP_001100823.1  sodium-dependent phosphate transport protein 3

    See identical proteins and their annotated locations for NP_001100823.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A6KLL4, A6KLL5, D4A3I8
    Related
    ENSRNOP00000023241.6, ENSRNOT00000023241.8
    Conserved Domains (2) summary
    cd06174
    Location:81 → 436
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:1 → 434
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    41748195..41767601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039095709.2 → XP_038951637.1  sodium-dependent phosphate transport protein 3 isoform X5

    Conserved Domains (1) summary
    cd17318
    Location:5 → 390
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  2. XM_006253967.5 → XP_006254029.1  sodium-dependent phosphate transport protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006254029.1

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:21 → 462
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  3. XM_039095707.2 → XP_038951635.1  sodium-dependent phosphate transport protein 3 isoform X5

    Conserved Domains (1) summary
    cd17318
    Location:5 → 390
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  4. XM_006253966.5 → XP_006254028.1  sodium-dependent phosphate transport protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006254028.1

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:21 → 462
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  5. XM_039095704.2 → XP_038951632.1  sodium-dependent phosphate transport protein 3 isoform X2

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:21 → 462
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  6. XM_039095706.2 → XP_038951634.1  sodium-dependent phosphate transport protein 3 isoform X4

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:1 → 439
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  7. XM_039095702.2 → XP_038951630.1  sodium-dependent phosphate transport protein 3 isoform X1

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:30 → 471
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  8. XM_039095705.2 → XP_038951633.1  sodium-dependent phosphate transport protein 3 isoform X3

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:30 → 443
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  9. XM_039095703.2 → XP_038951631.1  sodium-dependent phosphate transport protein 3 isoform X1

    UniProtKB/TrEMBL
    A6KLL4
    Conserved Domains (1) summary
    cd17318
    Location:30 → 471
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  10. XM_039095712.2 → XP_038951640.1  sodium-dependent phosphate transport protein 3 isoform X7

    Conserved Domains (1) summary
    cl28910
    Location:30 → 240
    MFS; Major Facilitator Superfamily

  11. XM_039095710.2 → XP_038951638.1  sodium-dependent phosphate transport protein 3 isoform X6

    Conserved Domains (1) summary
    cl28910
    Location:30 → 325
    MFS; Major Facilitator Superfamily

  12. XM_039095711.2 → XP_038951639.1  sodium-dependent phosphate transport protein 3 isoform X7

    Conserved Domains (1) summary
    cl28910
    Location:30 → 240
    MFS; Major Facilitator Superfamily

RNA

  1. XR_010058868.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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