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Cldn22 claudin 22 [ Rattus norvegicus (Norway rat) ]

Gene ID: 306454, updated on 2-Nov-2024

Summary

Official Symbol
Cldn22provided by RGD
Official Full Name
claudin 22provided by RGD
Primary source
RGD:1305271
See related
AllianceGenome:RGD:1305271
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN22 (claudin 22). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Cldn22 in Genome Data Viewer
Location:
16q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (51155058..51156084, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (44422344..44423370, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (47534349..47535358, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551022 Neighboring gene WW and C2 domain containing 2 Neighboring gene uncharacterized LOC134482501 Neighboring gene uncharacterized LOC134482379 Neighboring gene claudin 24 Neighboring gene proteasome subunit alpha type-5-like

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110143.2NP_001103613.1  claudin-22

    See identical proteins and their annotated locations for NP_001103613.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A6JPK2, D3ZEF2
    Conserved Domains (1) summary
    cl21598
    Location:49183
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    51155058..51156084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)