U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

csnk2a1 casein kinase 2, alpha 1 polypeptide [ Danio rerio (zebrafish) ]

Gene ID: 30502, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
csnk2a1provided by ZNC
Official Full Name
casein kinase 2, alpha 1 polypeptideprovided by ZNC
Primary source
ZFIN:ZDB-GENE-990415-27
See related
Ensembl:ENSDARG00000002082 AllianceGenome:ZFIN:ZDB-GENE-990415-27
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ck2a1; wu:fi38e04; wu:fi38h03
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in DNA damage response and regulation of cell cycle. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including CSNK2A1 (casein kinase 2 alpha 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See csnk2a1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (31436757..31452431, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (31478830..31494575, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene scleraxis bHLH transcription factor b Neighboring gene zgc:194210 Neighboring gene protein tyrosine phosphatase 4A3b Neighboring gene N-myc downstream regulated 1b

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Zebrafish wnt4b expression in the floor plate is altered in sonic hedgehog and gli-2 mutants. Liu A, et al. Mech Dev, 2000 Mar 1. PMID 10704875
  2. Dynamics of zebrafish fin regeneration using a pulsed SILAC approach. Nolte H, et al. Proteomics, 2015 Feb. PMID 25504979
  3. Gonad differentiation in zebrafish is regulated by the canonical Wnt signaling pathway. Sreenivasan R, et al. Biol Reprod, 2014 Feb. PMID 24174574
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA damage response IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein kinase CK2 complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
casein kinase II subunit alpha
Names
casein kinase 2 alpha 1
ck2 alpha
NP_571327.1
XP_005158227.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131252.1 → NP_571327.1  casein kinase II subunit alpha

    See identical proteins and their annotated locations for NP_571327.1

    Status: PROVISIONAL

    Source sequence(s)
    BC044403
    UniProtKB/TrEMBL
    B2GTG4, Q803N7
    Related
    ENSDARP00000006001.8, ENSDART00000008297.10
    Conserved Domains (2) summary
    cd14132
    Location:20 → 325
    STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2
    pfam00069
    Location:39 → 324
    Pkinase; Protein kinase domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    31436757..31452431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158170.4 → XP_005158227.1  casein kinase II subunit alpha isoform X1

    See identical proteins and their annotated locations for XP_005158227.1

    UniProtKB/TrEMBL
    B2GTG4, Q803N7
    Related
    ENSDARP00000056550.4, ENSDART00000056551.6
    Conserved Domains (2) summary
    cd14132
    Location:20 → 325
    STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2
    pfam00069
    Location:39 → 324
    Pkinase; Protein kinase domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394962.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    303572..319194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.