U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tbc1d9 TBC1 domain family member 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304645, updated on 10-Jul-2024

Summary

Go to the top of the page Help
Official Symbol
Tbc1d9provided by RGD
Official Full Name
TBC1 domain family member 9provided by RGD
Primary source
RGD:1308221
See related
EnsemblRapid:ENSRNOG00000003496 AllianceGenome:RGD:1308221
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308221
Summary
Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Orthologous to human TBC1D9 (TBC1 domain family member 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 123.5), Spleen (RPKM 46.7) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Tbc1d9 in Genome Data Viewer
Location:
19q11
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (41746732..41855924, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (24842166..24951383, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (24328381..24429908)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene ELMO domain containing 2 Neighboring gene uncoupling protein 1 Neighboring gene uncharacterized LOC134483334 Neighboring gene uncharacterized LOC108348918 Neighboring gene uncharacterized LOC102554553 Neighboring gene ring finger protein 150 Neighboring gene uncharacterized LOC134483336

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
TBC1 domain family member 9
Names
TBC1 domain family, member 9 (with GRAM domain)
vascular Rab-GAP/TBC-containing

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001415072.1 → NP_001402001.1  TBC1 domain family member 9

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/TrEMBL
    A0A8I5ZNC8, A6IYF7, D3ZXE3
    Related
    ENSRNOP00000063198.2, ENSRNOT00000065558.4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    41746732..41855924 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039097678.2 → XP_038953606.1  TBC1 domain family member 9 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K9K0
    Related
    ENSRNOP00000079826.2, ENSRNOT00000113408.2
    Conserved Domains (5) summary
    smart00164
    Location:504 → 714
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13354
    Location:298 → 393
    PH-GRAM2_TCB1D9_TCB1D9B; TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13351
    Location:151 → 249
    PH-GRAM1_TCB1D9_TCB1D9B; TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1
    cl08302
    Location:885 → 915
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl17169
    Location:938 → 1002
    RRM_SF; RNA recognition motif (RRM) superfamily

  2. XM_039097679.2 → XP_038953607.2  TBC1 domain family member 9 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K9K0
    Related
    ENSRNOP00000103191.1, ENSRNOT00000130407.1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001134539.2: Suppressed sequence

    Description
    NM_001134539.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools