kifc1 kinesin family member C1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: kifc1provided by ZNC
Official Full Name: kinesin family member C1provided by ZNC
Primary source: ZFIN:ZDB-GENE-000208-21
See related: Ensembl:ENSDARG00000001558 AllianceGenome:ZFIN:ZDB-GENE-000208-21
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: knsl2; fc27e02; fd14g02; wu:fc27e02; wu:fd14g02
Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement and mitotic spindle assembly. Predicted to be located in cytoskeleton. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in head. Orthologous to human KIFC1 (kinesin family member C1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human all
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Genomic context

Location:: chromosome: 19

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (6990971..7000727)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (7072052..7081597)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

fb75g08.y1 (e-PCR)
- UniSTS:191263

fc27e02.x1 (e-PCR)
- UniSTS:193357

fc27e02.x1 (e-PCR)
- UniSTS:193358

fd14g02.x1 (e-PCR)
- UniSTS:204180

fi69g07.x1 (e-PCR)
- UniSTS:197878

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule motor activity	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule motor activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in microtubule-based movement	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within microtubule-based movement	IEA Inferred from Electronic Annotation more info
involved_in mitotic spindle assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in system development	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
part_of kinesin complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in microtubule organizing center	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitotic spindle	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: kinesin-like protein KIFC1

Names: kinesin-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044954.2 → NP_001038419.1 kinesin-like protein KIFC1

See identical proteins and their annotated locations for NP_001038419.1

Status: VALIDATED

Source sequence(s)

FP102097

UniProtKB/TrEMBL

A0A8M2B6D9, A4QNZ0, Q1LUU7

Related

ENSDARP00000155080.1, ENSDART00000193566.1

Conserved Domains (2) summary

cd01366
Location:271 → 610

KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins

cl25732
Location:101 → 275

SMC_N; RecF/RecN/SMC N terminal domain
NM_131206.2 → NP_571281.2 kinesin-like protein KIFC1

Status: VALIDATED

Source sequence(s)

FP102097

UniProtKB/TrEMBL

A0A8M2B6D9, A4QNZ0, Q1LUU7

Related

ENSDARP00000139775.1, ENSDART00000160482.2

Conserved Domains (2) summary

cd01366
Location:271 → 610

KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins

cl25732
Location:101 → 275

SMC_N; RecF/RecN/SMC N terminal domain