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Cldn8 claudin 8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304124, updated on 2-Nov-2024

Summary

Official Symbol
Cldn8provided by RGD
Official Full Name
claudin 8provided by RGD
Primary source
RGD:1308575
See related
AllianceGenome:RGD:1308575
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in apicolateral plasma membrane and basolateral plasma membrane. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN8 (claudin 8). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Cldn8 in Genome Data Viewer
Location:
11q11
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (41362081..41364330, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (27875857..27878106, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (28525641..28527890, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene claudin 17 Neighboring gene KAT8 regulatory NSL complex subunit 2, pseudogene 1 Neighboring gene keratin associated protein 24-1 Neighboring gene keratin-associated protein 26-1-like

Genomic regions, transcripts, and products

General gene information

Markers

Clone Names

  • MGC124857

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in apicolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037774.1NP_001032863.1  claudin-8

    See identical proteins and their annotated locations for NP_001032863.1

    Status: PROVISIONAL

    Source sequence(s)
    BC099804
    UniProtKB/TrEMBL
    F7FAZ0, Q499Q7
    Conserved Domains (1) summary
    cl21598
    Location:5182
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    41362081..41364330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)