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Mmgt2 membrane magnesium transporter 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303211, updated on 17-Aug-2024

Summary

Official Symbol
Mmgt2provided by RGD
Official Full Name
membrane magnesium transporter 2provided by RGD
Primary source
RGD:1311260
See related
EnsemblRapid:ENSRNOG00000069117 AllianceGenome:RGD:1311260
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311260
Summary
Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be located in Golgi membrane and early endosome membrane. Predicted to be part of EMC complex. Predicted to be active in Golgi apparatus; early endosome; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 46.7), Heart (RPKM 40.1) and 9 other tissues See more
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Genomic context

See Mmgt2 in Genome Data Viewer
Location:
10q23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (47842722..47859787)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (47343446..47362889)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (48986163..48989596)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel, subfamily V, member 2 Neighboring gene small nucleolar RNA, C/D box 65 Neighboring gene leucine rich repeat containing 75A Neighboring gene uncharacterized LOC120095115 Neighboring gene zinc finger protein 287 Neighboring gene transfer RNA tryptophan (anticodon CCA) 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables inorganic cation transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables magnesium ion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in magnesium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in magnesium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of EMC complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of EMC complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in early endosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
membrane magnesium transporter 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013967.2NP_001013989.2  membrane magnesium transporter 2

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    Q6P719
    UniProtKB/TrEMBL
    A0A8I6A4V9, A6HFB7
    Related
    ENSRNOP00000085801.1, ENSRNOT00000102374.2
    Conserved Domains (1) summary
    pfam10270
    Location:2990
    MMgT; Membrane magnesium transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    47842722..47859787
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085969.2XP_038941897.1  membrane magnesium transporter 2 isoform X1

    UniProtKB/Swiss-Prot
    Q6P719
    UniProtKB/TrEMBL
    A0A8I6A4V9, A6HFB7
    Related
    ENSRNOP00000092726.1, ENSRNOT00000118425.2
    Conserved Domains (1) summary
    pfam10270
    Location:2990
    MMgT; Membrane magnesium transporter
  2. XM_039085971.2XP_038941899.1  membrane magnesium transporter 2 isoform X1

    UniProtKB/Swiss-Prot
    Q6P719
    UniProtKB/TrEMBL
    A0A8I6A4V9, A6HFB7
    Related
    ENSRNOP00000081126.1, ENSRNOT00000107468.2
    Conserved Domains (1) summary
    pfam10270
    Location:2990
    MMgT; Membrane magnesium transporter