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Mrpl42 mitochondrial ribosomal protein L42 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299743, updated on 2-Nov-2024

Summary

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Official Symbol
Mrpl42provided by RGD
Official Full Name
mitochondrial ribosomal protein L42provided by RGD
Primary source
RGD:1304915
See related
EnsemblRapid:ENSRNOG00000042740 AllianceGenome:RGD:1304915
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mrps32
Summary
Predicted to be located in mitochondrion and plasma membrane. Predicted to be part of mitochondrial large ribosomal subunit and mitochondrial small ribosomal subunit. Orthologous to human MRPL42 (mitochondrial ribosomal protein L42). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 471.4), Muscle (RPKM 419.9) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mrpl42 in Genome Data Viewer
Location:
7q13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (32004863..32028640, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (30117977..30141757, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (36573654..36597497, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene suppressor of cytokine signaling 2 Neighboring gene uncharacterized LOC134479868 Neighboring gene proteasome subunit alpha type-4-like Neighboring gene uncharacterized LOC102556774 Neighboring gene ubiquitin-conjugating enzyme E2N

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mammalian mitochondrial ribosomal proteins. N-terminal amino acid sequencing, characterization, and identification of corresponding gene sequences. Goldschmidt-Reisin S, et al. J Biol Chem, 1998 Dec 25. PMID 9857009
  2. The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. Cavdar Koc E, et al. J Biol Chem, 2001 Jun 1. PMID 11279123
  3. Structures of the human mitochondrial ribosome in native states of assembly. Brown A, et al. Nat Struct Mol Biol, 2017 Oct. PMID 28892042, Free PMC Article
  4. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
28S ribosomal protein L42, mitochondrial; large ribosomal subunit protein mL42
Names
28S ribosomal protein S32, mitochondrial
39S ribosomal protein L42, mitochondrial
L42mt
MRP-L42
MRP-S32
Mitochondrial 28S ribosomal protein S32, mitochondrial
S32mt

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106782.1 → NP_001100252.1  28S ribosomal protein L42, mitochondrial

    See identical proteins and their annotated locations for NP_001100252.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473960
    UniProtKB/TrEMBL
    A0A8I5ZJH6, A6IG39, B5DEP4, F7FFN1
    Related
    ENSRNOP00000102311.1, ENSRNOT00000128223.1
    Conserved Domains (1) summary
    pfam10210
    Location:45 → 141
    MRP-S32; Mitochondrial 28S ribosomal protein S32

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    32004863..32028640 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008765315.4 → XP_008763537.1  large ribosomal subunit protein mL42 isoform X1

    See identical proteins and their annotated locations for XP_008763537.1

    UniProtKB/TrEMBL
    A0A8I5ZJH6, A6IG39, B5DEP4, F7FFN1
    Conserved Domains (1) summary
    pfam10210
    Location:45 → 141
    MRP-S32; Mitochondrial 28S ribosomal protein S32

  2. XM_063263205.1 → XP_063119275.1  large ribosomal subunit protein mL42 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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