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Washc3 WASH complex subunit 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299707, updated on 10-Oct-2024

Summary

Official Symbol
Washc3provided by RGD
Official Full Name
WASH complex subunit 3provided by RGD
Primary source
RGD:1563761
See related
EnsemblRapid:ENSRNOG00000005102 AllianceGenome:RGD:1563761
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ccdc53; RGD1563761
Summary
Predicted to be involved in actin filament polymerization and exocytosis. Predicted to be part of WASH complex. Orthologous to human WASHC3 (WASH complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 325.7), Testes (RPKM 235.5) and 9 other tissues See more
Orthologs
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Genomic context

See Washc3 in Genome Data Viewer
Location:
7q13
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (24508544..24553012)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (22621078..22665550)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (28762417..28809286)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene nucleoporin 37 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene uncharacterized LOC120093767 Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 32 Neighboring gene uncharacterized LOC134479855

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in actin filament polymerization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of WASH complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of WASH complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
WASH complex subunit 3
Names
WASH complex subunit CCDC53
coiled-coil domain containing 53

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106776.1NP_001100246.1  WASH complex subunit 3

    See identical proteins and their annotated locations for NP_001100246.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473960
    UniProtKB/TrEMBL
    A0A8I6ATX8, A6IFN5, D3ZKX1
    Conserved Domains (1) summary
    pfam10152
    Location:30167
    CCDC53; Subunit CCDC53 of WASH complex

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    24508544..24553012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006241199.5XP_006241261.1  WASH complex subunit 3 isoform X1

    UniProtKB/TrEMBL
    A0A8I6ATX8
    Related
    ENSRNOP00000096775.2, ENSRNOT00000107294.2
    Conserved Domains (1) summary
    pfam10152
    Location:30166
    CCDC53; Subunit CCDC53 of WASH complex
  2. XM_063263195.1XP_063119265.1  WASH complex subunit 3 isoform X2

  3. XM_039078687.2XP_038934615.1  WASH complex subunit 3 isoform X3

    UniProtKB/TrEMBL
    A0A8I6GIR0
    Conserved Domains (1) summary
    pfam10152
    Location:30144
    CCDC53; Subunit CCDC53 of WASH complex