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Rpl7a ribosomal protein L7A [ Rattus norvegicus (Norway rat) ]

Gene ID: 296596, updated on 28-Oct-2024

Summary

Official Symbol
Rpl7aprovided by RGD
Official Full Name
ribosomal protein L7Aprovided by RGD
Primary source
RGD:1307586
See related
EnsemblRapid:ENSRNOG00000070974 AllianceGenome:RGD:1307586
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in cellular response to Thyroid stimulating hormone. Located in ribosome. Part of cytosolic large ribosomal subunit. Orthologous to human RPL7A (ribosomal protein L7a). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Thymus (RPKM 11.1), Spleen (RPKM 8.4) and 9 other tissues See more
Orthologs
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Genomic context

See Rpl7a in Genome Data Viewer
Location:
3p13
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (30637136..30639778)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (10239026..10241703)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (5458985..5461627)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene surfeit 6 Neighboring gene mediator complex subunit 22 Neighboring gene small nucleolar RNA SNORD36 Neighboring gene small nucleolar RNA SNORD36 Neighboring gene small nucleolar RNA SNORD36 Neighboring gene small nucleolar RNA, C/D box 24 Neighboring gene SURF1, cytochrome c oxidase assembly factor Neighboring gene surfeit 2 Neighboring gene surfeit 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to Thyroid stimulating hormone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in ribosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in ribosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large ribosomal subunit protein eL8
Names
60S ribosomal protein L7a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114391.1NP_001107863.1  large ribosomal subunit protein eL8

    See identical proteins and their annotated locations for NP_001107863.1

    Status: PROVISIONAL

    Source sequence(s)
    BC159421
    UniProtKB/Swiss-Prot
    P62425
    UniProtKB/TrEMBL
    A6JTI5, B0K021, B1WC55, D3ZU22, F1M013, F2Z3S2
    Related
    ENSRNOP00000063128.4, ENSRNOT00000044551.6
    Conserved Domains (1) summary
    PTZ00365
    Location:16266
    PTZ00365; 60S ribosomal protein L7Ae-like; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    30637136..30639778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)