Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ugt2b37provided by RGD
Official Full Name: UDP-glucuronosyltransferase 2 family, member 37provided by RGD
Primary source: RGD:3937
See related: EnsemblRapid:ENSRNOG00000081572 AllianceGenome:RGD:3937
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Enables glucuronosyltransferase activity. Predicted to be involved in cellular glucuronidation and estrogen metabolic process. Predicted to be located in endoplasmic reticulum membrane. Orthologous to several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B11 (UDP glucuronosyltransferase family 2 member B11); and UGT2B15 (UDP glucuronosyltransferase family 2 member B15). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 2375.9) See more
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Genomic context

Location:: 14p21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (21172136..21188768)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (20817285..20833917)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (22495084..22534865)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables glucuronosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucuronosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables glucuronosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellular glucuronidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in estrogen metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-glucuronosyltransferase 2B37

Names: 17-beta-hydroxysteroid specific; 17-beta-hydroxysteroid-specific UDPGT; UDP-glucuronosyltransferase 2 family, member 5; UDP-glucuronosyltransferase 2B5; UDP-glucuronosyltransferase R-21; UDPGT 2B37; UDPGT 2B5; UDPGTr-21; UDPGTr-5

NP_001007265.4

EC 2.4.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007264.4 → NP_001007265.4 UDP-glucuronosyltransferase 2B37 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000014

UniProtKB/Swiss-Prot

P19488, P19489

UniProtKB/TrEMBL

F1M7N8

Related

ENSRNOP00000109960.1, ENSRNOT00000130103.1

Conserved Domains (1) summary

pfam00201
Location:24 → 527

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase