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Fam227b family with sequence similarity 227, member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 296118, updated on 2-Nov-2024

Summary

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Official Symbol
Fam227bprovided by RGD
Official Full Name
family with sequence similarity 227, member Bprovided by RGD
Primary source
RGD:1359452
See related
EnsemblRapid:ENSRNOG00000037124 AllianceGenome:RGD:1359452
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1359452
Summary
Orthologous to human FAM227B (family with sequence similarity 227 member B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 600.7), Kidney (RPKM 70.2) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam227b in Genome Data Viewer
Location:
3q36
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (133686602..133845793, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (113226662..113392396, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (118268631..118427878, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene SECIS binding protein 2-like Neighboring gene TATA element modulatory factor 1, pseudogene 1 Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene fibroblast growth factor 7 Neighboring gene DTW domain containing 1 Neighboring gene ATPase phospholipid transporting 8B4 (putative) Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC108954

General protein information

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Preferred Names
protein FAM227B
Names
uncharacterized protein C15orf33 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013920.2 → NP_001013942.2  protein FAM227B

    See identical proteins and their annotated locations for NP_001013942.2

    Status: VALIDATED

    Source sequence(s)
    BC089861, CK653446
    UniProtKB/Swiss-Prot
    Q5FVN5, Q6AXP3
    UniProtKB/TrEMBL
    A0A8I6AC49
    Related
    ENSRNOP00000052849.4, ENSRNOT00000055995.4
    Conserved Domains (2) summary
    pfam14922
    Location:144 → 293
    FWWh; Protein of unknown function
    cl00240
    Location:405 → 492
    RRF; Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another round of ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    133686602..133845793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234909.5 → XP_006234971.2  protein FAM227B isoform X1

  2. XM_039104564.2 → XP_038960492.1  protein FAM227B isoform X2

    Conserved Domains (1) summary
    pfam14922
    Location:148 → 293
    FWWh; Protein of unknown function
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AXP3.2 GenPept UniProtKB/Swiss-Prot:Q6AXP3

Gene LinkOut

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