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lepA translation elongation factor 4 [ Brucella melitensis bv. 1 str. 16M ]

Gene ID: 29595477, updated on 31-Mar-2024

Summary

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Gene symbol
lepA
Gene description
translation elongation factor 4
Locus tag
BME_RS11460
Gene type
protein coding
Organism
Brucella melitensis bv. 1 str. 16M (strain: 16M, biovar: 1 str. 16M, type-material: type strain of Brucella melitensis)
Lineage
Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales; Brucellaceae; Brucella/Ochrobactrum group; Brucella
Old locus tag
BMEII0260
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Genomic context

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Location:
chromosome: II
Sequence:
Chromosome: II; NC_003318.1 (272810..274618)

Chromosome II - NC_003318.1Genomic Context describing neighboring genes Neighboring gene undecaprenyl-diphosphate phosphatase Neighboring gene complex I NDUFA9 subunit family protein Neighboring gene GIY-YIG nuclease family protein Neighboring gene SelT/SelW/SelH family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003318.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Whole-genome sequences of 24 Brucella strains. Minogue TD, et al. Genome Announc, 2014 Sep 18. PMID 25237024, Free PMC Article
  2. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
  3. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
  4. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article
  5. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
translation elongation factor 4
WP_004682459.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003318.1 Reference assembly

    Range
    272810..274618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004682459.1 MULTISPECIES: translation elongation factor 4 [Brucella]

    See identical proteins and their annotated locations for WP_004682459.1

    UniProtKB/Swiss-Prot
    C0RMH8, Q8YDB8
    UniProtKB/TrEMBL
    A0A9P2TXC0
    Conserved Domains (1) summary
    PRK05433
    Location:2 → 602
    PRK05433; GTP-binding protein LepA; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8YDB8.1