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Msto1 misato mitochondrial distribution and morphology regulator 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295237, updated on 2-Nov-2024

Summary

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Official Symbol
Msto1provided by RGD
Official Full Name
misato mitochondrial distribution and morphology regulator 1provided by RGD
Primary source
RGD:1306110
See related
EnsemblRapid:ENSRNOG00000020357 AllianceGenome:RGD:1306110
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306110
Summary
Predicted to be involved in mitochondrion distribution. Predicted to be located in cytosol and mitochondrial outer membrane. Predicted to be active in mitochondrion. Orthologous to human MSTO1 (misato mitochondrial distribution and morphology regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 43.6), Testes (RPKM 43.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Msto1 in Genome Data Viewer
Location:
2q34
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176603755..176608037, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174305945..174310230, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188212211..188216482, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene Ras-like without CAAX 1 Neighboring gene synaptotagmin 11 Neighboring gene gon-4 like Neighboring gene death associated protein 3 Neighboring gene ASH1 like histone lysine methyltransferase Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Human Misato regulates mitochondrial distribution and morphology. Kimura M, et al. Exp Cell Res, 2007 Apr 15. PMID 17349998
  2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in mitochondrion distribution ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrion organization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
protein misato homolog 1
Names
misato 1, mitochondrial distribution and morphology regulator
misato homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106443.1 → NP_001099913.1  protein misato homolog 1

    See identical proteins and their annotated locations for NP_001099913.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473976
    UniProtKB/TrEMBL
    A6J6A9, A6J6B0, D3ZMW3
    Related
    ENSRNOP00000027579.4, ENSRNOT00000027579.6
    Conserved Domains (1) summary
    cd06060
    Location:6 → 547
    misato; Misato segment II tubulin-like domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    176603755..176608037 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102035.2 → XP_038957963.1  protein misato homolog 1 isoform X1

    UniProtKB/TrEMBL
    A6J6A9
    Conserved Domains (1) summary
    cd06060
    Location:6 → 587
    misato; Misato segment II tubulin-like domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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