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CCFHVsSgp1 nucleoprotein [ Orthonairovirus haemorrhagiae ]

Gene ID: 2943076, updated on 18-Aug-2023

Summary

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Gene symbol
CCFHVsSgp1
Gene description
nucleoprotein
Locus tag
CCFHVsSgp1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Orthonairovirus haemorrhagiae (strain: 10200)
Lineage
Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; Ellioviricetes; Bunyavirales; Nairoviridae; Orthonairovirus
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Genomic context

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Location:
segment: S
Sequence:
NC_005302.1 (56..1504)

NC_005302.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_005302.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crimean-Congo Hemorrhagic Fever Virus Nucleocapsid Protein Augments mRNA Translation. Jeeva S, et al. J Virol, 2017 Aug 1. PMID 28515298, Free PMC Article
  2. Structure, function, and evolution of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein. Carter SD, et al. J Virol, 2012 Oct. PMID 22875964, Free PMC Article
  3. Structure of Crimean-Congo hemorrhagic fever virus nucleoprotein: superhelical homo-oligomers and the role of caspase-3 cleavage. Wang Y, et al. J Virol, 2012 Nov. PMID 22951837, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Crimean-Congo hemorrhagic fever virus nucleoprotein binds to the viral mRNA 5' untranslated region (UTR) with high affinity. It facilitates the translation of reporter mRNA both in vivo and in vitro with the assistance of the viral mRNA 5' UTR.
    Title: Crimean-Congo Hemorrhagic Fever Virus Nucleocapsid Protein Augments mRNA Translation.
  2. cleavage of CCHFV N by host cell caspase-3 appears to be crucial for controlling viral RNA synthesis
    Title: Structure of Crimean-Congo hemorrhagic fever virus nucleoprotein: superhelical homo-oligomers and the role of caspase-3 cleavage.
  3. solved crystal structure of the CCHFV strain Baghdad-12 nucleocapsid protein (N) at a resolution of 2.1 A; observations suggest a structural flexibility that may provide the basis for switching between alternative N protein conformations during important functions such as RNA binding and oligomerization
    Title: Structure, function, and evolution of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein.
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General gene information

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Homology

General protein information

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Preferred Names
nucleoprotein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_005302.1 Reference assembly

    Range
    56..1504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_950237.1 nucleoprotein [Orthonairovirus haemorrhagiae]

    See identical proteins and their annotated locations for NP_950237.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P89522
    UniProtKB/TrEMBL
    A0A1V0G0G8, Q0P0H8
    Conserved Domains (1) summary
    pfam02477
    Location:1 → 441
    Nairo_nucleo; Nucleocapsid N protein
Protein Accession Links
GenPept Link UniProtKB Link
AAB48501.1
ARB51456.1
AWX63619.1

Gene LinkOut

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Molecular Biology Databases
Research Materials