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Vwa3a von Willebrand factor A domain containing 3A [ Rattus norvegicus (Norway rat) ]

Gene ID: 293449, updated on 2-Nov-2024

Summary

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Official Symbol
Vwa3aprovided by RGD
Official Full Name
von Willebrand factor A domain containing 3Aprovided by RGD
Primary source
RGD:1311670
See related
EnsemblRapid:ENSRNOG00000025110 AllianceGenome:RGD:1311670
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311670
Summary
Orthologous to human VWA3A (von Willebrand factor A domain containing 3A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 47.3), Testes (RPKM 34.9) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Vwa3a in Genome Data Viewer
Location:
1q36
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (184725106..184786884)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (175293782..175355588)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (190679722..190742444)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene modulator of smoothened Neighboring gene large ribosomal subunit protein uL10-like Neighboring gene uncharacterized LOC102555900 Neighboring gene uncharacterized LOC120099921 Neighboring gene short chain dehydrogenase/reductase family 42E, member 2 Neighboring gene transfer RNA leucine (anticodon UAG) 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC156760

General protein information

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Preferred Names
von Willebrand factor A domain-containing protein 3A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079885.1 → NP_001073354.1  von Willebrand factor A domain-containing protein 3A isoform 2

    See identical proteins and their annotated locations for NP_001073354.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple 3' exons and has an alternate 3' end, as compared to variant 1. The resulting isoform (2) is much shorter than isoform 1 at the C-terminus.
    Source sequence(s)
    BC128762
    UniProtKB/Swiss-Prot
    A1A5Q7
    UniProtKB/TrEMBL
    A0A8I5ZM94
    Related
    ENSRNOP00000079157.1, ENSRNOT00000102809.2
    Conserved Domains (1) summary
    cl00057
    Location:143 → 297
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  2. NM_001198653.1 → NP_001185582.1  von Willebrand factor A domain-containing protein 3A isoform 1

    See identical proteins and their annotated locations for NP_001185582.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6I8S2, F1M1K0
    Conserved Domains (2) summary
    cd00198
    Location:923 → 1073
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl00057
    Location:143 → 297
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    184725106..184786884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230159.5 → XP_006230221.1  von Willebrand factor A domain-containing protein 3A isoform X9

    UniProtKB/TrEMBL
    F1M1K0
    Related
    ENSRNOP00000032210.7, ENSRNOT00000036175.7
    Conserved Domains (2) summary
    cd00198
    Location:930 → 1080
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl00057
    Location:143 → 297
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  2. XM_063285910.1 → XP_063141980.1  von Willebrand factor A domain-containing protein 3A isoform X1

  3. XM_063285917.1 → XP_063141987.1  von Willebrand factor A domain-containing protein 3A isoform X3

  4. XM_039107079.2 → XP_038963007.1  von Willebrand factor A domain-containing protein 3A isoform X5

    UniProtKB/TrEMBL
    A6I8S3
    Conserved Domains (1) summary
    cl00057
    Location:142 → 297
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  5. XM_039107074.2 → XP_038963002.1  von Willebrand factor A domain-containing protein 3A isoform X4

    UniProtKB/TrEMBL
    A6I8S3
    Conserved Domains (1) summary
    cl00057
    Location:142 → 297
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  6. XM_039107082.2 → XP_038963010.1  von Willebrand factor A domain-containing protein 3A isoform X6

    UniProtKB/TrEMBL
    A0A8I5ZM94
    Conserved Domains (1) summary
    cl00057
    Location:142 → 297
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  7. XM_063285923.1 → XP_063141993.1  von Willebrand factor A domain-containing protein 3A isoform X7

    Related
    ENSRNOP00000107280.1, ENSRNOT00000166387.1

  8. XM_063285926.1 → XP_063141996.1  von Willebrand factor A domain-containing protein 3A isoform X8

  9. XM_063285913.1 → XP_063141983.1  von Willebrand factor A domain-containing protein 3A isoform X2

RNA

  1. XR_010065632.1 RNA Sequence

  2. XR_005503151.2 RNA Sequence

  3. XR_005503154.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1A5Q7.1 GenPept UniProtKB/Swiss-Prot:A1A5Q7

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