IGLV3-25 immunoglobulin lambda variable 3-25 [Homo sapiens (human)] - Gene

Summary

Official Symbol: IGLV3-25provided by HGNC
Official Full Name: immunoglobulin lambda variable 3-25provided by HGNC
Primary source: HGNC:HGNC:5908
See related: Ensembl:ENSG00000211659 IMGT/GENE-DB:IGLV3-25; AllianceGenome:HGNC:5908
Gene type: other
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: V2-17; IGLV325
Summary: Predicted to be involved in immune response. Located in blood microparticle. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 22q11.22

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	22	NC_000022.11 (22686769..22687281)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	22	NC_060946.1 (23109779..23110291)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	22	NC_000022.10 (23029233..23029745)

Chromosome 22 - NC_000022.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH102691 (e-PCR)
- UniSTS:97025

RH48178 (e-PCR)
- UniSTS:37128

STS-N26665 (e-PCR)
- UniSTS:67087

STS-AA017564 (e-PCR)
- UniSTS:20758

D22S1243 (e-PCR)
- UniSTS:54812

D22S556 (e-PCR)
- UniSTS:45614

RH70693 (e-PCR)
- UniSTS:4143

D22S655 (e-PCR)
- UniSTS:149814

D22S425 (e-PCR), detects polymorphism
- UniSTS:84031

WIAF-2521 (e-PCR)
- UniSTS:89926

D22S425 (e-PCR), detects polymorphism
- UniSTS:71242

D22S686 (e-PCR), detects polymorphism
- UniSTS:79693

RH93749 (e-PCR)
- UniSTS:86101

D22S563 (e-PCR)
- UniSTS:55903

RH71387 (e-PCR)
- UniSTS:15712

D22S940 (e-PCR)
- UniSTS:150369

D22S1587 (e-PCR)
- UniSTS:473698

D22S1114 (e-PCR)
- UniSTS:28773

D8S463 (e-PCR)
- UniSTS:14695

D22S1543 (e-PCR)
- UniSTS:62567

RH71381 (e-PCR)
- UniSTS:13673

G54039 (e-PCR)
- UniSTS:109421

IGLC6 (e-PCR)
- UniSTS:266610

PRAME_9364 (e-PCR)
- UniSTS:468616

STS-M34515 (e-PCR)
- UniSTS:27280

STS-X51755 (e-PCR)
- UniSTS:16533

G18165 (e-PCR)
- UniSTS:59042

RH71286 (e-PCR)
- UniSTS:12708

RH71287 (e-PCR)
- UniSTS:12709

D22S1040 (e-PCR)
- UniSTS:38058

SUHW2__5350 (e-PCR)
- UniSTS:464576

GDB:452623 (e-PCR)
- UniSTS:157397

D22S593 (e-PCR)
- UniSTS:41943

RH122997 (e-PCR)
- UniSTS:135389

RH45724 (e-PCR)
- UniSTS:15335

SHGC-57080 (e-PCR)
- UniSTS:33257

GDB:190925 (e-PCR)
- UniSTS:155633

SHGC-81766 (e-PCR)
- UniSTS:103925

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables antigen binding	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info
involved_in immune response	NAS Non-traceable Author Statement more info	PubMed
involved_in immunoglobulin production	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in blood microparticle	HDA more info	PubMed
located_in extracellular region	NAS Non-traceable Author Statement more info	PubMed
located_in extracellular region	TAS Traceable Author Statement more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
part_of immunoglobulin complex	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	TAS Traceable Author Statement more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.