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Tp53i13 tumor protein p53 inducible protein 13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287550, updated on 2-Nov-2024

Summary

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Official Symbol
Tp53i13provided by RGD
Official Full Name
tumor protein p53 inducible protein 13provided by RGD
Primary source
RGD:1559818
See related
EnsemblRapid:ENSRNOG00000022615 AllianceGenome:RGD:1559818
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Trp53i13; RGD1559818
Summary
Predicted to be involved in several processes, including negative regulation of cell cycle; response to UV; and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human TP53I13 (tumor protein p53 inducible protein 13). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 79.2), Lung (RPKM 73.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tp53i13 in Genome Data Viewer
Location:
10q24
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (62854851..62861241, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (62356722..62363122, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (62650640..62655327)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 13B Neighboring gene uncharacterized LOC120095265 Neighboring gene GIT ArfGAP 1 Neighboring gene abhydrolase domain containing 15 Neighboring gene TAO kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. DSCP1, a novel TP53-inducible gene, is upregulated by strong genotoxic stresses and its overexpression inhibits tumor cell growth in vitro. Hata T, et al. Int J Oncol, 2004 Mar. PMID 14767535
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in negative regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in response to UV ISO
Inferred from Sequence Orthology
more info
  
involved_in response to organic cyclic compound ISO
Inferred from Sequence Orthology
more info
  
involved_in response to xenobiotic stimulus ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tumor protein p53-inducible protein 13
Names
transformation related protein 53 inducible protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105818.1 → NP_001099288.1  tumor protein p53-inducible protein 13 precursor

    See identical proteins and their annotated locations for NP_001099288.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473948
    UniProtKB/Swiss-Prot
    B0BN44
    UniProtKB/TrEMBL
    A6HGY3
    Related
    ENSRNOP00000010691.6, ENSRNOT00000010691.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    62854851..62861241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039085537.2 → XP_038941465.1  tumor protein p53-inducible protein 13 isoform X2

    UniProtKB/TrEMBL
    A6HGY4

  2. XM_063268685.1 → XP_063124755.1  tumor protein p53-inducible protein 13 isoform X2

    UniProtKB/TrEMBL
    A6HGY4

  3. XM_063268684.1 → XP_063124754.1  tumor protein p53-inducible protein 13 isoform X2

    UniProtKB/TrEMBL
    A6HGY4

  4. XM_006246902.5 → XP_006246964.1  tumor protein p53-inducible protein 13 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZWV6
    Related
    ENSRNOP00000083262.1, ENSRNOT00000094189.2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B0BN44.1 GenPept UniProtKB/Swiss-Prot:B0BN44

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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