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NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 [ Bos taurus (domestic cattle) ]

Gene ID: 287327, updated on 10-Oct-2024

Summary

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Official Symbol
NDUFS3provided by VGNC
Official Full Name
NADH:ubiquinone oxidoreductase core subunit S3provided by VGNC
Primary source
VGNC:VGNC:50228
See related
BGD:BT15899; Ensembl:ENSBTAG00000018483
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See NDUFS3 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (77378793..77383890)

Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene CUGBP Elav-like family member 1 Neighboring gene protein tyrosine phosphatase mitochondrial 1 Neighboring gene kelch repeat and BTB domain containing 4 Neighboring gene family with sequence similarity 180 member B Neighboring gene C1q and TNF related 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The 30-kilodalton subunit of bovine mitochondrial complex I is homologous to a protein coded in chloroplast DNA. Pilkington SJ, et al. Biochemistry, 1991 Feb 19. PMID 1899621
  2. The amino acid sequences of two 13 kDa polypeptides and partial amino acid sequence of 30 kDa polypeptide of complex I from bovine heart mitochondria: possible location of iron-sulfur clusters. Masui R, et al. J Biochem, 1991 Apr. PMID 1907966
  3. Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits. Carroll J, et al. J Biol Chem, 2002 Dec 27. PMID 12381726
  4. Architecture of mammalian respiratory complex I. Vinothkumar KR, et al. Nature, 2014 Nov 6. PMID 25209663, Free PMC Article
  5. Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme. Sazanov LA, et al. Biochemistry, 2000 Jun 20. PMID 10852722

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. subunits of complex I and two subcomplexes (Ialpha and Ibeta) were resolved on one- and two-dimensional gels and by reverse-phase high performance liquid chromatography
    Title: Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADH dehydrogenase (ubiquinone) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
Names
CI-30kD
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NADH-ubiquinone oxidoreductase 30 kDa subunit
complex I-30kD
NP_777244.1
XP_059730562.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174819.3 → NP_777244.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor

    See identical proteins and their annotated locations for NP_777244.1

    Status: PROVISIONAL

    Source sequence(s)
    M58469
    UniProtKB/TrEMBL
    F1MS25
    Related
    ENSBTAP00000024600.5, ENSBTAT00000024600.5
    Conserved Domains (1) summary
    PRK06074
    Location:60 → 242
    PRK06074; NADH dehydrogenase subunit C; Provisional

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    77378793..77383890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059874579.1 → XP_059730562.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23709.1 GenPept UniProtKB/Swiss-Prot:P23709

Gene LinkOut

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