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NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 [ Bos taurus (domestic cattle) ]

Gene ID: 287014, updated on 4-Oct-2024

Summary

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Official Symbol
NDUFV1provided by VGNC
Official Full Name
NADH:ubiquinone oxidoreductase core subunit V1provided by VGNC
Primary source
VGNC:VGNC:31974
See related
BGD:BT27787; Ensembl:ENSBTAG00000021776
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See NDUFV1 in Genome Data Viewer
Location:
chromosome: 29
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (45462753..45468972)

Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase pi 1 Neighboring gene glutathione S-transferase pi 1 Neighboring gene double C2 domain gamma Neighboring gene nudix hydrolase 8 Neighboring gene T-box transcription factor 10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cDNA-derived amino acid sequence of the NADH-binding 51-kDa subunit of the bovine respiratory NADH dehydrogenase reveals striking similarities to a bacterial NAD(+)-reducing hydrogenase. Patel SD, et al. Proc Natl Acad Sci U S A, 1991 May 15. PMID 2034666, Free PMC Article
  2. Structure of mammalian respiratory complex I. Zhu J, et al. Nature, 2016 Aug 18. PMID 27509854, Free PMC Article
  3. Relationship between mitochondrial NADH-ubiquinone reductase and a bacterial NAD-reducing hydrogenase. Pilkington SJ, et al. Biochemistry, 1991 Feb 26. PMID 1900194
  4. Architecture of mammalian respiratory complex I. Vinothkumar KR, et al. Nature, 2014 Nov 6. PMID 25209663, Free PMC Article
  5. Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme. Sazanov LA, et al. Biochemistry, 2000 Jun 20. PMID 10852722

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC139751

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADH dehydrogenase (ubiquinone) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Names
CI-51kD
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NADH dehydrogenase flavoprotein 1
NADH dehydrogenase ubiquinone flavoprotein 1
NADH-ubiquinone oxidoreductase 51 kDa subunit
complex I-51kD
NP_777233.1
XP_010819350.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174808.1 → NP_777233.1  NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor

    See identical proteins and their annotated locations for NP_777233.1

    Status: PROVISIONAL

    Source sequence(s)
    M58607
    UniProtKB/TrEMBL
    A0A3Q1MG52
    Related
    ENSBTAP00000070140.2, ENSBTAT00000075840.2
    Conserved Domains (4) summary
    PRK13596
    Location:35 → 449
    PRK13596; NADH dehydrogenase I subunit F; Provisional
    pfam01512
    Location:80 → 249
    Complex1_51K; Respiratory-chain NADH dehydrogenase 51 Kd subunit
    pfam10531
    Location:275 → 327
    SLBB; SLBB domain
    pfam10589
    Location:366 → 447
    NADH_4Fe-4S; NADH-ubiquinone oxidoreductase-F iron-sulfur binding region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    45462753..45468972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010821048.3 → XP_010819350.1  NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A452DJ13
    Related
    ENSBTAP00000029026.5, ENSBTAT00000029026.5
    Conserved Domains (4) summary
    PRK13596
    Location:92 → 506
    PRK13596; NADH dehydrogenase I subunit F; Provisional
    pfam01512
    Location:137 → 306
    Complex1_51K; Respiratory-chain NADH dehydrogenase 51 Kd subunit
    pfam10531
    Location:332 → 384
    SLBB; SLBB domain
    pfam10589
    Location:423 → 504
    NADH_4Fe-4S; NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25708.2 GenPept UniProtKB/Swiss-Prot:P25708

Gene LinkOut

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Molecular Biology Databases
Research Materials