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PREP prolyl endopeptidase [ Bos taurus (domestic cattle) ]

Gene ID: 286818, updated on 4-Oct-2024

Summary

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Official Symbol
PREPprovided by VGNC
Official Full Name
prolyl endopeptidaseprovided by VGNC
Primary source
VGNC:VGNC:33310
See related
BGD:BT20501; Ensembl:ENSBTAG00000016281
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PREP in Genome Data Viewer
Location:
chromosome: 9
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (44576174..44708317)

Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346107 Neighboring gene small ribosomal subunit protein eS25-like Neighboring gene HIG1 domain family member 1A, mitochondrial-like Neighboring gene popeye domain containing 3 Neighboring gene uncharacterized LOC112448050 Neighboring gene blood vessel epicardial substance

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and expression of the cDNA encoding prolyl oligopeptidase (prolyl endopeptidase) from bovine brain. Yoshimoto T, et al. Biol Pharm Bull, 1997 Oct. PMID 9353562
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC139175

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oligopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prolyl endopeptidase
Names
PE
post-proline cleaving enzyme
prolyl oligopeptidase
NP_777197.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174772.1 → NP_777197.1  prolyl endopeptidase

    See identical proteins and their annotated locations for NP_777197.1

    Status: PROVISIONAL

    Source sequence(s)
    AB028866
    UniProtKB/Swiss-Prot
    Q9XTA2
    UniProtKB/TrEMBL
    A5D7C6
    Related
    ENSBTAP00000065243.1, ENSBTAT00000077452.1
    Conserved Domains (2) summary
    COG1505
    Location:26 → 704
    PreP; Prolyl oligopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism]
    pfam00326
    Location:488 → 707
    Peptidase_S9; Prolyl oligopeptidase family

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    44576174..44708317
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XTA2.1 GenPept UniProtKB/Swiss-Prot:Q9XTA2

Gene LinkOut

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Molecular Biology Databases
Research Materials