PTPRN protein tyrosine phosphatase receptor type N [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PTPRNprovided by VGNC
Official Full Name: protein tyrosine phosphatase receptor type Nprovided by VGNC
Primary source: VGNC:VGNC:33554
See related: BGD:BT16507; Ensembl:ENSBTAG00000013798
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (107236822..107256178, complement)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_8095-8096:996688286:1 (e-PCR)
- UniSTS:269893

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in secretory granule	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: receptor-type tyrosine-protein phosphatase-like N

Names: ICA512; R-PTP-N; islet cell autoantigen 512

NP_001068599.1

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001075131.1 → NP_001068599.1 receptor-type tyrosine-protein phosphatase-like N precursor

See identical proteins and their annotated locations for NP_001068599.1

Status: PROVISIONAL

Source sequence(s)

BC119839

UniProtKB/Swiss-Prot

P56722, Q0VD45

UniProtKB/TrEMBL

A0A3Q1LX78

Related

ENSBTAP00000018336.3, ENSBTAT00000018336.4

Conserved Domains (4) summary

smart00194
Location:709 → 968

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:736 → 968

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

pfam11548
Location:472 → 557

Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2

pfam14948
Location:60 → 138

RESP18; RESP18 domain