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CTBP1-AS CTBP1 antisense RNA [ Homo sapiens (human) ]

Gene ID: 285463, updated on 10-Oct-2023

Summary

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Official Symbol
CTBP1-ASprovided by HGNC
Official Full Name
CTBP1 antisense RNAprovided by HGNC
Primary source
HGNC:HGNC:48337
See related
Ensembl:ENSG00000280927 AllianceGenome:HGNC:48337
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PCAT10
Expression
Ubiquitous expression in duodenum (RPKM 7.9), spleen (RPKM 7.5) and 25 other tissues See more
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Genomic context

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Location:
4p16.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (1210120..1218591)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (1209315..1217754)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (1203908..1212379)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene nascent polypeptide-associated complex subunit alpha, muscle-specific form-like Neighboring gene hornerin-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:1143546-1144046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:1144047-1144547 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21143 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:1160925-1161208 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:1165551-1166266 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:1166267-1166984 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21145 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:1172226-1172726 Neighboring gene spondin 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:1188097-1188808 Neighboring gene uncharacterized LOC100130872 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr4:1190349-1191548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:1193431-1193980 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21146 Neighboring gene uncharacterized LOC124900164 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21147 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21148 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15123 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21149 Neighboring gene C-terminal binding protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:1227715-1228270 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:1233764-1234264 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15124 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15125 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21150 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21151 Neighboring gene CTBP1 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21152 Neighboring gene uncharacterized LOC105374347 Neighboring gene uncharacterized LOC105374346

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. CTBP1‑AS upregulation is associated with polycystic ovary syndrome and can be effectively downregulated by cryptotanshinone. Wen M, et al. Mol Med Rep, 2022 Jul. PMID 35656892, Free PMC Article
  2. Androgen receptor coregulator long noncoding RNA CTBP1-AS is associated with polycystic ovary syndrome in Kashmiri women. Nabi M, et al. Endocrine, 2022 Feb. PMID 34611799
  3. Molecular mechanisms of long chain non-coding RNA CTBP1-AS in regulation of invasion and migration of breast cancer cells. Cui HB, et al. J Biol Regul Homeost Agents, 2019 May-Jun,. PMID 31165609
  4. Androgen Receptor Coregulator CTBP1-AS Is Associated With Polycystic Ovary Syndrome in Chinese Women: A Preliminary Study. Liu Z, et al. Reprod Sci, 2015 Jul. PMID 25552498, Free PMC Article
  5. Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. Takayama K, et al. EMBO J, 2013 Jun 12. PMID 23644382, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CTBP1AS upregulation is associated with polycystic ovary syndrome and can be effectively downregulated by cryptotanshinone.
    Title: CTBP1‑AS upregulation is associated with polycystic ovary syndrome and can be effectively downregulated by cryptotanshinone.
  2. Androgen receptor coregulator long noncoding RNA CTBP1-AS is associated with polycystic ovary syndrome in Kashmiri women.
    Title: Androgen receptor coregulator long noncoding RNA CTBP1-AS is associated with polycystic ovary syndrome in Kashmiri women.
  3. Overexpressed LncRNA CTBP1-AS promoted breast cancer cell proliferation, invasion as well as migration, inhibited cell apoptosis and accelerated breast cancer development by sponging microRNA-940.
    Title: Molecular mechanisms of long chain non-coding RNA CTBP1-AS in regulation of invasion and migration of breast cancer cells.
  4. CTBP1-AS, a novel androgen receptor regulator, is associated with polycystic ovary syndrome in Chinese women.
    Title: Androgen Receptor Coregulator CTBP1-AS Is Associated With Polycystic Ovary Syndrome in Chinese Women: A Preliminary Study.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • prostate cancer associated transcript 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_104331.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC092535, AK092548
    Related
    ENST00000625256.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    1210120..1218591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    1209315..1217754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Research Materials