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folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD [ Picrophilus oshimae DSM 9789 ]

Gene ID: 2845254, updated on 22-Oct-2024

Summary

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Gene symbol
folD
Gene description
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Locus tag
PTO_RS05640
Gene type
protein coding
Organism
Picrophilus oshimae DSM 9789 (strain: DSM 9790, type-material: type strain of Picrophilus torridus)
Lineage
Archaea; Methanobacteriati; Thermoplasmatota; Thermoplasmata; Thermoplasmatales; Picrophilaceae; Picrophilus
Old locus tag
PTO1071
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Genomic context

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Sequence:
NC_005877.1 (1081861..1082691)

NC_005877.1Genomic Context describing neighboring genes Neighboring gene SAM-dependent methyltransferase Neighboring gene carboxymuconolactone decarboxylase family protein Neighboring gene glucose/galactose 1-dehydrogenase Neighboring gene YidH family protein Neighboring gene ketol-acid reductoisomerase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_005877.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Lee WH, et al. Biochem Biophys Res Commun, 2011 Mar 18. PMID 21333632
  2. Cloning, sequencing and expression of the gene encoding glucose dehydrogenase from the thermophilic archaeon Thermoplasma acidophilum. Bright JR, et al. Eur J Biochem, 1993 Feb 1. PMID 8436115
  3. Genome sequence of Picrophilus torridus and its implications for life around pH 0. Fütterer O, et al. Proc Natl Acad Sci U S A, 2004 Jun 15. PMID 15184674, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
WP_011177872.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_005877.1 Reference assembly

    Range
    1081861..1082691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011177872.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD [Picrophilus oshimae]

    See identical proteins and their annotated locations for WP_011177872.1

    UniProtKB/Swiss-Prot
    Q6L046
    Conserved Domains (3) summary
    COG0190
    Location:1 → 273
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    pfam00763
    Location:2 → 115
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
    pfam02882
    Location:118 → 273
    THF_DHG_CYH_C; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6L046.1

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