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LINC00663 long intergenic non-protein coding RNA 663 [ Homo sapiens (human) ]

Gene ID: 284440, updated on 10-Oct-2023

Summary

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Official Symbol
LINC00663provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 663provided by HGNC
Primary source
HGNC:HGNC:28609
See related
MIM:617117; AllianceGenome:HGNC:28609
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 1.9), ovary (RPKM 1.5) and 24 other tissues See more
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Genomic context

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Location:
19p13.11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (19756371..19776413, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (19894039..19914115, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (19867180..19887222, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 14 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10457 Neighboring gene uncharacterized LOC101060187 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:19858409-19858910 Neighboring gene sorting nexin 18 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14370 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:19887366-19888257 Neighboring gene zinc finger protein 56, pseudogene Neighboring gene zinc finger protein 506 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14372 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:19932265-19932779 Neighboring gene iron-sulfur cluster assembly 1 pseudogene 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The Effect and Mechanism of LINC00663 on the Biological Behavior of Glioma. Pan M, et al. Neurochem Res, 2021 Jul. PMID 33830405
  2. A novel variable exonic region and differential expression of LINC00663 non-coding RNA in various cancer cell lines and normal human tissue samples. Bozgeyik E, et al. Tumour Biol, 2016 Jul. PMID 26743782
  3. Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma. Igci YZ, et al. Endocr Pathol, 2011 Jun. PMID 21509594
  4. DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. Nowak M, et al. J Cell Sci, 2019 Sep 6. PMID 31391242
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Effect and Mechanism of LINC00663 on the Biological Behavior of Glioma.
    Title: The Effect and Mechanism of LINC00663 on the Biological Behavior of Glioma.
  2. LINC00663 was shown to be differentially expressed in various human tissues and cancer cell lines.
    Title: A novel variable exonic region and differential expression of LINC00663 non-coding RNA in various cancer cell lines and normal human tissue samples.
  3. LOC284440 gene expression is decreased in follicular variant of papillary thyroid carcinoma.
    Title: Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Potential readthrough

Included gene: ZNF506

Other Names

  • CTC-559E9.1

Clone Names

  • FLJ12356, MGC39821

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_026956.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC011477, AK289657, BC034236, DB196080

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    19756371..19776413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    19894039..19914115 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_182576.1: Suppressed sequence

    Description
    NM_182576.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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