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CSNK1A1 casein kinase 1 alpha 1 [ Bos taurus (domestic cattle) ]

Gene ID: 282684, updated on 4-Oct-2024

Summary

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Official Symbol
CSNK1A1provided by VGNC
Official Full Name
casein kinase 1 alpha 1provided by VGNC
Primary source
VGNC:VGNC:55205
See related
BGD:BT25775; Ensembl:ENSBTAG00000005326
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CSNK1A1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (60856710..60906241, complement)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345768 Neighboring gene microRNA mir-143 Neighboring gene microRNA mir-145 Neighboring gene Rho guanine nucleotide exchange factor 37 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene PPARG coactivator 1 beta Neighboring gene microRNA mir-378-1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Development of a biosensor immunoassay for the quantification of alphas1-casein in milk. Muller-Renaud S, et al. J Dairy Res, 2005 Feb. PMID 15747732
  2. Isolation and solubilization of casein kinase from Golgi apparatus of bovine mammary gland and phosphorylation of peptides. Szymanski ES, et al. Biochim Biophys Acta, 1982 Apr 3. PMID 6952938
  3. Purification of casein kinase I and isolation of cDNAs encoding multiple casein kinase I-like enzymes. Rowles J, et al. Proc Natl Acad Sci U S A, 1991 Nov 1. PMID 1946367, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sensitivy of a biosensor to detect alphas1-CN concentrations ranging from 8.8 to 12.06 mg/ml.
    Title: Development of a biosensor immunoassay for the quantification of alphas1-casein in milk.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC133860

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
casein kinase I isoform alpha; casein kinase I
Names
CK1
CKI-alpha
casein kinase I-alpha
NP_777136.1
XP_005209607.1
XP_005209608.1
XP_005209609.1
XP_005209610.1
XP_005209611.1
XP_005209613.1
XP_005209614.1
XP_010805724.1
XP_024849629.1
XP_024849630.1
XP_024849631.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174711.2 → NP_777136.1  casein kinase I isoform alpha

    See identical proteins and their annotated locations for NP_777136.1

    Status: PROVISIONAL

    Source sequence(s)
    M76543
    UniProtKB/Swiss-Prot
    P67827, Q9GLY1, Q9GLY2, Q9GLY3
    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 281
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    60856710..60906241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005209556.5 → XP_005209613.1  casein kinase I isoform X10

    See identical proteins and their annotated locations for XP_005209613.1

    UniProtKB/TrEMBL
    A0AAA9TJX7, A0AAF6YNF5
    Related
    ENSBTAP00000096556.1, ENSBTAT00000113060.1
    Conserved Domains (1) summary
    cd14128
    Location:16 → 281
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  2. XM_005209554.5 → XP_005209611.1  casein kinase I isoform X7

    See identical proteins and their annotated locations for XP_005209611.1

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  3. XM_005209551.5 → XP_005209608.1  casein kinase I isoform X4

    See identical proteins and their annotated locations for XP_005209608.1

    UniProtKB/TrEMBL
    A0AAA9TPT0, A0AAF6YNF5
    Related
    ENSBTAP00000098382.1, ENSBTAT00000118261.1
    Conserved Domains (1) summary
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  4. XM_024993861.2 → XP_024849629.1  casein kinase I isoform X3

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  5. XM_024993862.2 → XP_024849630.1  casein kinase I isoform X8

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 281
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  6. XM_010807422.3 → XP_010805724.1  casein kinase I isoform X1

    UniProtKB/TrEMBL
    A0A3Q1LK11, A0AAF6YNF5
    Related
    ENSBTAP00000056925.1, ENSBTAT00000086663.2
    Conserved Domains (2) summary
    COG0515
    Location:16 → 267
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  7. XM_005209557.2 → XP_005209614.1  casein kinase I isoform X11

    See identical proteins and their annotated locations for XP_005209614.1

    UniProtKB/TrEMBL
    A0AAF6YNF5, Q32LI4
    Related
    ENSBTAP00000035028.2, ENSBTAT00000035150.3
    Conserved Domains (1) summary
    cd14128
    Location:16 → 281
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  8. XM_024993863.2 → XP_024849631.1  casein kinase I isoform X9

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Related
    ENSBTAP00000007007.4, ENSBTAT00000007007.5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 281
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  9. XM_005209553.2 → XP_005209610.1  casein kinase I isoform X6

    See identical proteins and their annotated locations for XP_005209610.1

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  10. XM_005209550.2 → XP_005209607.1  casein kinase I isoform X2

    See identical proteins and their annotated locations for XP_005209607.1

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

  11. XM_005209552.2 → XP_005209609.1  casein kinase I isoform X5

    See identical proteins and their annotated locations for XP_005209609.1

    UniProtKB/TrEMBL
    A0AAF6YNF5
    Conserved Domains (1) summary
    cd14128
    Location:16 → 309
    STKc_CK1_alpha; Catalytic domain of the Serine/Threonine protein kinases, Casein Kinase 1 alpha

RNA

  1. XR_003035337.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P67827.1 GenPept UniProtKB/Swiss-Prot:P67827

Gene LinkOut

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