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UQCRC2 ubiquinol-cytochrome c reductase core protein 2 [ Bos taurus (domestic cattle) ]

Gene ID: 282394, updated on 4-Oct-2024

Summary

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Official Symbol
UQCRC2provided by VGNC
Official Full Name
ubiquinol-cytochrome c reductase core protein 2provided by VGNC
Primary source
VGNC:VGNC:36696
See related
BGD:BT18324; Ensembl:ENSBTAG00000021651
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See UQCRC2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (19647330..19673877)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 14 Neighboring gene ATP binding cassette subfamily A member 16 Neighboring gene large ribosomal subunit protein uL30-like Neighboring gene PDZ domain containing 9 Neighboring gene modulator of smoothened Neighboring gene U6 spliceosomal RNA Neighboring gene von Willebrand factor A domain containing 3A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Complexity and tissue specificity of the mitochondrial respiratory chain. Capaldi RA, et al. J Bioenerg Biomembr, 1988 Jun. PMID 2841307
  2. Subunit arrangement in beef heart complex III. González-Halphen D, et al. Biochemistry, 1988 Sep 6. PMID 2848575
  3. Fertility-related proteomic profiling bull spermatozoa separated by percoll. Park YJ, et al. J Proteome Res, 2012 Aug 3. PMID 22794312
  4. Core I protein of bovine ubiquinol-cytochrome-c reductase; an additional member of the mitochondrial-protein-processing family. Cloning of bovine core I and core II cDNAs and primary structure of the proteins. Gencic S, et al. Eur J Biochem, 1991 Jul 1. PMID 1712295
  5. Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria. Xia D, et al. Science, 1997 Jul 4. PMID 9204897

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ENO1, VDAC2, and UQCRC2 were significantly correlated with individual fertility in bulls.
    Title: Fertility-related proteomic profiling bull spermatozoa separated by percoll.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytochrome b-c1 complex subunit 2, mitochondrial
Names
complex III subunit 2
core protein II
ubiquinol-cytochrome c reductase core protein II
ubiquinol-cytochrome-c reductase complex core protein 2
NP_001357536.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370607.1 → NP_001357536.1  cytochrome b-c1 complex subunit 2, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    NKLS02000025
    UniProtKB/Swiss-Prot
    P23004, Q3ZCG7, Q5E9C7
    UniProtKB/TrEMBL
    A0A3Q1M7H9
    Related
    ENSBTAP00000028853.4, ENSBTAT00000028853.6
    Conserved Domains (1) summary
    COG0612
    Location:26 → 434
    PqqL; Predicted Zn-dependent peptidase [General function prediction only]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19647330..19673877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23004.2 GenPept UniProtKB/Swiss-Prot:P23004

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.