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ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 [ Bos taurus (domestic cattle) ]

Gene ID: 282352, updated on 4-Oct-2024

Summary

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Official Symbol
ST8SIA1provided by VGNC
Official Full Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:49964
See related
BGD:BT27720; Ensembl:ENSBTAG00000000593
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
SIAT8A
Orthologs
human mouse all
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Genomic context

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See ST8SIA1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (87876164..88059386)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene ethanolamine kinase 1 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene C2 calcium dependent domain containing 5 Neighboring gene large ribosomal subunit protein uL16-like Neighboring gene uncharacterized LOC132345330 Neighboring gene sulfotransferase 6B1-like Neighboring gene cytidine monophosphate N-acetylneuraminic acid synthetase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-glycan processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in oligosaccharide metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Names
GD3 synthase
SIAT8-A
ST8Sia I
ST8SiaI
alpha-2,8-sialyltransferase 1
alpha-2,8-sialyltransferase 8A
alpha-N-acetylneuraminate: alpha-2,8-sialytransferase
ganglioside GD3 synthase
ganglioside GT3 synthase
sialyltransferase 8A
sialyltransferase St8Sia I
sialytransferase St8Sia I
NP_001027470.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032299.1 → NP_001027470.1  alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

    See identical proteins and their annotated locations for NP_001027470.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ699418
    UniProtKB/Swiss-Prot
    Q6ZXD2
    UniProtKB/TrEMBL
    F1MRQ8
    Related
    ENSBTAP00000067376.1, ENSBTAT00000074715.2
    Conserved Domains (1) summary
    pfam00777
    Location:92 → 344
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    87876164..88059386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003034555.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZXD2.1 GenPept UniProtKB/Swiss-Prot:Q6ZXD2

Gene LinkOut

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Molecular Biology Databases
Research Materials