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PPP3R1 protein phosphatase 3 regulatory subunit B, alpha [ Bos taurus (domestic cattle) ]

Gene ID: 282321, updated on 17-Aug-2024

Summary

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Official Symbol
PPP3R1provided by VGNC
Official Full Name
protein phosphatase 3 regulatory subunit B, alphaprovided by VGNC
Primary source
VGNC:VGNC:50247
See related
BGD:BT30320; Ensembl:ENSBTAG00000010619
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PPP3R1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (66605841..66667488, complement)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal assembly factor 10 Neighboring gene partner of NOB1 homolog Neighboring gene cannabinoid receptor interacting protein 1 Neighboring gene pleckstrin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation and characterization of a cDNA clone coding for the calcium-binding subunit of calcineurin from bovine brain: an identical amino acid sequence to the human protein. Nargang CE, et al. DNA Seq, 1994. PMID 7803816
  2. The structure of the B subunit of calcineurin. Aitken A, et al. Eur J Biochem, 1984 Mar 15. PMID 6321184
  3. Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Klee CB, et al. Proc Natl Acad Sci U S A, 1979 Dec. PMID 293720, Free PMC Article
  4. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Liu J, et al. Cell, 1991 Aug 23. PMID 1715244
  5. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Griffith JP, et al. Cell, 1995 Aug 11. PMID 7543369

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calcineurin subunit B type 1
Names
calcineurin B
protein phosphatase 2B regulatory subunit 1
NP_777008.1
XP_059747007.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174583.2 → NP_777008.1  calcineurin subunit B type 1

    See identical proteins and their annotated locations for NP_777008.1

    Status: PROVISIONAL

    Source sequence(s)
    X71666
    UniProtKB/Swiss-Prot
    P63099
    UniProtKB/TrEMBL
    A0AAA9TX86
    Related
    ENSBTAP00000102960.1, ENSBTAT00000125997.1
    Conserved Domains (1) summary
    COG5126
    Location:13 → 157
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    66605841..66667488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059891024.1 → XP_059747007.1  calcineurin subunit B type 1 isoform X1

    UniProtKB/TrEMBL
    A0AAA9TX86
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P63099.2 GenPept UniProtKB/Swiss-Prot:P63099

Gene LinkOut

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