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RBBP6 RB binding protein 6, ubiquitin ligase [ Bos taurus (domestic cattle) ]

Gene ID: 282034, updated on 4-Oct-2024

Summary

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Official Symbol
RBBP6provided by VGNC
Official Full Name
RB binding protein 6, ubiquitin ligaseprovided by VGNC
Primary source
VGNC:VGNC:33771
See related
BGD:BT22672; Ensembl:ENSBTAG00000009441
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See RBBP6 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (22200338..22235875)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene protein kinase C beta Neighboring gene uncharacterized LOC107131818 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 3 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene 5'-AMP-activated protein kinase subunit gamma-1-like Neighboring gene trinucleotide repeat containing adaptor 6A Neighboring gene solute carrier family 5 member 11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative analysis of 82 expressed sequence tags from a cattle ovary cDNA library. Ma RZ, et al. Mamm Genome, 1998 Jul. PMID 9657852
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RBBP6
Names
retinoblastoma-binding protein 6
NP_001291483.1
XP_005224863.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304554.1 → NP_001291483.1  E3 ubiquitin-protein ligase RBBP6

    See identical proteins and their annotated locations for NP_001291483.1

    Status: VALIDATED

    Source sequence(s)
    CN437095, DT816727, DV851977, EH156083, EH179135, NKLS02000025
    UniProtKB/TrEMBL
    A0AAA9RXX2, E1BCZ2
    Related
    ENSBTAP00000077429.1, ENSBTAT00000090719.1
    Conserved Domains (4) summary
    smart00184
    Location:259 → 299
    RING; Ring finger
    COG5222
    Location:2 → 419
    COG5222; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    pfam08783
    Location:4 → 75
    DWNN; DWNN domain
    pfam13696
    Location:156 → 176
    zf-CCHC_2; Zinc knuckle

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    22200338..22235875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005224806.4 → XP_005224863.1  E3 ubiquitin-protein ligase RBBP6 isoform X1

    UniProtKB/TrEMBL
    A0AAA9SUX1, E1BCZ2
    Related
    ENSBTAP00000086970.1, ENSBTAT00000108590.1
    Conserved Domains (4) summary
    smart00184
    Location:259 → 299
    RING; Ring finger
    COG5222
    Location:2 → 419
    COG5222; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    pfam08783
    Location:4 → 75
    DWNN; DWNN domain
    pfam13696
    Location:156 → 176
    zf-CCHC_2; Zinc knuckle
Nucleotide Protein Strain
Heading Accession and Version

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