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PRKCG protein kinase C gamma [ Bos taurus (domestic cattle) ]

Gene ID: 282002, updated on 10-Oct-2024

Summary

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Official Symbol
PRKCGprovided by VGNC
Official Full Name
protein kinase C gammaprovided by VGNC
Primary source
VGNC:VGNC:33331
See related
BGD:BT12246; Ensembl:ENSBTAG00000013550
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PRKCG in Genome Data Viewer
Location:
chromosome: 18
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (61578930..61602874)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene cationic amino acid transporter 3-like Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene myeloid associated differentiation marker Neighboring gene arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 7 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 8 Neighboring gene microRNA mir-935

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nishizuka Y. Nature, 1988 Aug 25. PMID 3045562
  2. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Coussens L, et al. Science, 1986 Aug 22. PMID 3755548
  3. Comparative mapping of anchor loci from HSA19 to cattle chromosomes 7 and 18. Gao Q, et al. J Hered, 1997 Nov-Dec. PMID 9419894
  4. Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressors, 4E-binding proteins. Whalen SG, et al. J Biol Chem, 1996 May 17. PMID 8662663
  5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein kinase C gamma type
Names
PKC-gamma
putative protein kinase C gamma type
NP_001159974.1
XP_015313861.1
XP_059732495.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166502.2 → NP_001159974.1  protein kinase C gamma type

    See identical proteins and their annotated locations for NP_001159974.1

    Status: VALIDATED

    Source sequence(s)
    DAAA02047724, DV888979, M13976
    UniProtKB/Swiss-Prot
    P05128
    UniProtKB/TrEMBL
    A0AAA9T335
    Related
    ENSBTAP00000090895.1, ENSBTAT00000094081.1
    Conserved Domains (4) summary
    cd04026
    Location:158 → 289
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05587
    Location:354 → 677
    STKc_cPKC; Catalytic domain of the Serine/Threonine Kinase, Classical (or Conventional) Protein Kinase C
    cd20833
    Location:34 → 91
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:101 → 154
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61578930..61602874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059876512.1 → XP_059732495.1  protein kinase C gamma type isoform X1

  2. XM_015458375.3 → XP_015313861.1  protein kinase C gamma type isoform X2

    UniProtKB/Swiss-Prot
    P05128
    UniProtKB/TrEMBL
    A0AAA9T335
    Related
    ENSBTAP00000018020.6, ENSBTAT00000018020.6
    Conserved Domains (4) summary
    cd04026
    Location:158 → 289
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05587
    Location:354 → 677
    STKc_cPKC; Catalytic domain of the Serine/Threonine Kinase, Classical (or Conventional) Protein Kinase C
    cd20833
    Location:34 → 91
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:101 → 154
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P05128.1 GenPept UniProtKB/Swiss-Prot:P05128

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