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MYO1C myosin IC [ Bos taurus (domestic cattle) ]

Gene ID: 281937, updated on 12-Oct-2024

Summary

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Official Symbol
MYO1Cprovided by VGNC
Official Full Name
myosin ICprovided by VGNC
Primary source
VGNC:VGNC:31818
See related
BGD:BT27292; Ensembl:ENSBTAG00000001332
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
MMIb
Orthologs
human mouse all
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Genomic context

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See MYO1C in Genome Data Viewer
Location:
chromosome: 19
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (22596197..22620365, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene CRK proto-oncogene, adaptor protein Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene geranylgeranyl transferase type-2 subunit beta-like Neighboring gene inositol polyphosphate-5-phosphatase K Neighboring gene uncharacterized LOC132343030

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells. Fan Y, et al. J Cell Biol, 2012 Jul 9. PMID 22778278, Free PMC Article
  2. A novel myosin I from bovine adrenal gland. Zhu T, et al. FEBS Lett, 1994 Feb 14. PMID 8313976
  3. Domain structure of a mammalian myosin I beta. Reizes O, et al. Proc Natl Acad Sci U S A, 1994 Jul 5. PMID 8022785, Free PMC Article
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microfilament motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vesicle transport along actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microvillus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
unconventional myosin-Ic
Names
MMI-beta
myosin I beta
myosin-Ic

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174396.3 → NP_776821.3  unconventional myosin-Ic

    See identical proteins and their annotated locations for NP_776821.3

    Status: VALIDATED

    Source sequence(s)
    BC140534, U03420
    UniProtKB/Swiss-Prot
    A5D7F3, Q27966, Q28138
    UniProtKB/TrEMBL
    A0AAF6Z9W3
    Related
    ENSBTAP00000073868.1, ENSBTAT00000085502.2
    Conserved Domains (3) summary
    smart00015
    Location:756 → 776
    IQ; Calmodulin-binding motif
    cd01378
    Location:62 → 718
    MYSc_Myo1; class I myosin, motor domain
    pfam06017
    Location:874 → 1055
    Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    22596197..22620365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005220065.4 → XP_005220122.1  unconventional myosin-Ic isoform X3

    See identical proteins and their annotated locations for XP_005220122.1

    UniProtKB/TrEMBL
    A0AAF6Z9W3
    Related
    ENSBTAP00000029554.4, ENSBTAT00000029555.5
    Conserved Domains (3) summary
    smart00015
    Location:721 → 741
    IQ; Calmodulin-binding motif
    cd01378
    Location:27 → 683
    MYSc_Myo1; class I myosin, motor domain
    pfam06017
    Location:839 → 1020
    Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

  2. XM_059877721.1 → XP_059733704.1  unconventional myosin-Ic isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M3N4
    Related
    ENSBTAP00000068133.1, ENSBTAT00000084801.2

  3. XM_005220064.2 → XP_005220121.1  unconventional myosin-Ic isoform X2

    UniProtKB/TrEMBL
    A0AAF6Z9W3
    Related
    ENSBTAP00000029553.6, ENSBTAT00000029554.6
    Conserved Domains (3) summary
    smart00015
    Location:737 → 757
    IQ; Calmodulin-binding motif
    cd01378
    Location:43 → 699
    MYSc_Myo1; class I myosin, motor domain
    pfam06017
    Location:855 → 1036
    Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27966.3 GenPept UniProtKB/Swiss-Prot:Q27966

Gene LinkOut

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