CEBPA CCAAT enhancer binding protein alpha [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: CEBPA
Gene description: CCAAT enhancer binding protein alpha
See related: Ensembl:ENSBTAG00000065802
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	18	NC_037345.1 (43728248..43729478, complement)

Chromosome 18 - NC_037345.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Investigation of high correlation with carcass traits of SNPs of the PLCB1, C/EBPalpha, and TDRKH genes and the combinations of SNPs using the MDR method in the Hanwoo.
Title: Investigation of high correlation with carcass traits of SNPs of the PLCB1, C/EBPα, and TDRKH genes and the combinations of SNPs using the MDR method in the Hanwoo.
ACOX1, regulated by C/EBPalpha and miR-25-3p, promotes bovine preadipocyte adipogenesis.
Title: ACOX1, regulated by C/EBPα and miR-25-3p, promotes bovine preadipocyte adipogenesis.
These results suggest that the CEBPA gene is a strong candidate gene that affects carcass traits in Qinchuan cattle.
Title: Effect of genetic variation of CEBPA gene on body measurement and carcass traits of Qinchuan cattle.
Expressions of C-EBPalpha and myostatin in muscles were higher in the concentrate-fed group than in the grass hay-fed group.
Title: Influence of different feeding systems on the growth performance and muscle development of Japanese Black steers.

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General gene information

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Markers

CEBPA (e-PCR)
- UniSTS:278192

Cebpa (e-PCR), detects polymorphism
- UniSTS:527283

WI-16546 (e-PCR)
- UniSTS:45508

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in myeloid cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: CCAAT/enhancer-binding protein alpha

Names: CCAAT/enhancer binding protein (C/EBP), alpha; c/EBP alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_176784.2 → NP_789741.2 CCAAT/enhancer-binding protein alpha

See identical proteins and their annotated locations for NP_789741.2

Status: PROVISIONAL

Source sequence(s)

AY458599

UniProtKB/Swiss-Prot

O02754, Q4PLC3

UniProtKB/TrEMBL

Q6SI70

Related

ENSBTAP00000086425.1, ENSBTAT00000116686.1

Conserved Domains (1) summary

cd14711
Location:275 → 335

bZIP_CEBPA; Basic leucine zipper (bZIP) domain of CCAAT/enhancer-binding protein alpha (CEBPA): a DNA-binding and dimerization domain